Note: crushing the 23 mg tablet may significantly increase the rate of absorption; the 5 mg and 10 mg tablets are not affected. NEEMMC GUIDELINES FOR TABLET CRUSHING AND ADMINISTRATION VIA ENTERAL FEEDING TUBES KEY TO DRUG ADMINISTRATION GUIDELINES Please follow the guidelines in order, as shown in the chart (i.e. Ampicillin is a prescription penicillin-type antibiotic used to treat many different types of infections caused by bacteria, such as ear infections, bladder infections, pneumonia, gonorrhea, and E. coli or salmonella infection. Do not chew or crush the contents of the capsule. Arymo ER (morphine) Tablet. Medications requiring special safeguards to reduce the risk of errors and minimize harm. A Tablet will disperse in 1-2 minutes. Note: Sublingual tablet; do not suck, chew, or swallow whole.Slow-release; Note: contents are intended to be sprinkled on food or liquid but should not be chewed or crushed.Film-coated; tablet is scored and may be split; Note: 150 mg tablets can be broken into two-thirds or one-third to provide a 100 mg and 50 mg strength, respectivelySlow-release; Note: this lollipop delivery system requires the patient to slowly allow dissolution. Enteric-coated. Enter the terms you wish to search for. /���<0�``���w/_|y��xW������>�x�V�,��彍[�z�������M���4k
�Z5��҄�*���h^n�G���{7��t,G���F���_%���|���G���a��Q�$d����&lT�q>�����h�v��)čoC(3?n995J?U�� Ampicillin oral capsule is used to treat infections that are caused by certain types of bacteria. Crushing tablets may have repercussions on the licensed status of the medicine and how the medicine may affect the patient. Dangerous Wrong-Route Errors with Tranexamic Acid Do not swallow the capsule. %PDF-1.5
This list has been adapted with permission from Echaiz, T. A. %����
B Tablet will disperse in greater than 2 minutes. Medications requiring special safeguards to reduce the risk of errors and minimize harm. Please check with a pharmacist for further advice if necessary. number 1 is the first choice of which form to administer the drug in). The person who crushes the tablets or opens the capsules is exposed to drug particles, which may be carcinogenic, teratogenic or fetotoxic. endobj
All rights reserved. When a gastro-resistant layer is destroyed by crushing, underdosing is likely. If chewed and swallowed, may result in a lower peak concentration and bioavailability.Irritant; Note: chewed, crushed, or sucked tablets may cause oropharyngeal ulceration.Note: crushing the 23 mg tablet may significantly increase the rate of absorption; the 5 mg and 10 mg tablets are not affectedSlow-release; Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal dose.Slow-release; Note: chewed, cut, or crushed tablets may cause oropharyngeal irritationMucous membrane irritation; Note: drug may cause fetal abnormalities; women who are, or may become, pregnant, should not handle capsules; all women should use caution in handling capsules, especially leaking capsulesSublingual form (g); Note: chewing or swallowing may result in lower bioavailability.Note: chewed, crushed, or sucked tablets may cause oropharyngeal irritationAntineoplastic; Note: crushed or broken tablets should not be handledNote: chewing or swallowing may result in lower peak concentrations and bioavailabilitySlow-release; Note: may expose to potentially fatal overdoseNote: tablets should be dispersed completely in waterNote: although not in the package insert, the drug has a coating that is intended to release the drug over approximately 3 hoursNote: capsules may be opened and the contents mixed with food/drinkSlow-release; Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal dose.Slow-release (a) (Note: may add contents of capsule to chilled, not warm, applesauce and consume immediately)Slow-release; oral disintegrating tablet designed to disintegrate on the tongue.Taste; Note: capsule may be opened and mixed with fruit puree (e.g., banana)Note: drug may be crushed but company recommends using injectionNote: exposure to the powder may cause serious skin toxicities; health care workers should wear gloves to administerSlow-release (a); Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal doseNote: package insert indicates potential teratogenic effects; material safety data sheet warns against skin contact; health care workers should take appropriate precautionsSlow-release (Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal dose)Note: do not give as whole tablet, tablets are meant to be given as oral suspension; see company insertMucous membrane irritant; Note: may be dissolved in water or apple juiceNote: not scored; no studies available from companyNote: exposure to the powder may cause serious skin toxicities; health care workers should wear gloves to administerSlow-release; Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal doseAntineoplastic; Note: not scored; no studies available from companySlow-release (h); Note: 30mg tablet may not be splitNote: not scored; no studies available from companyNote: tablet should be swallowed whole and not crushed; tablet may be dispersed in waterNote: tablet may be dissolved in 4-8 ounces of waterNote: see prescribing information for making a suspensionMucous membrane irritant; Note: women who are, or may become, pregnant, should not handle crushed or broken tablets (l)Slow-release (a) (Note: do not give via NG tubes; crushing, chewing or dissolving tablets can cause rapid release and absorption of a potentially fatal dose)Note: not scored; no studies available from companyTaste (b) (Note: some extemporaneous formulas are pharmacy prepared)Slow-release (Note: tablet matrix may remain in stool)Slow-release (b); Note: crushing, chewing or dissolving tablets can cause rapid release and absorption of a potentially fatal doseSlow-release (b); Note: crushing, chewing or dissolving tablets can cause rapid release and absorption of a potentially fatal doseNote: crushing tablets has resulted in decreased bioavailability of drug (b)Slow-release; Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal doseSlow-release; Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal doseNote: not amenable to crushing; may obstruct feeding tubes (b)Slow-release; Note: crushing, chewing, or dissolving tablets can cause rapid release and absorption of a potentially fatal doseNote: breaking, chewing, or emptying contents of the capsule can result in increased exposureNote: see package insert for administration instructions via an oral syringe of NG tubeNote: pharmacokinetics may be altered if not taken wholeNote: women who are, or may become, pregnant, should not handle crushed or broken tabletsNote: women who are, or may become, pregnant, should not handle crushed or broken tabletsNote: pharmacokinetic parameters may be affected (b)Slow-release; Note: delayed release is dependent on an intact coating (b)Note: Teratogenic potential; health care workers should avoid contact with capsule contents/body fluidsNote: an oral powder is available, see prescribing information for administration instructionsNote: tablets are not scored and cutting may cause variable dosage accuracyNote: exposure to the powder may cause serious skin toxicities; health care workers should wear gloves to administerFilm-coated (Note: active ingredients are surrounded by wax matrix to prevent healthcare exposure; women who are, or may become, pregnant should not handle crushed or broken tablet)Note: combining multiple tablets or portions of tablets may lead to an overdose of entacaponeNote: disruption of capsule may yield high blood levels causing enhanced toxicity (a)Empty contents into a spoon for administration.