Do not use a larger amount or use it more often than directed. The following information includes only the average doses of this medicine. If so, consult your doctor about the potential risks and benefits before using this medicine. To do so may cause irritation of the skin.Do not apply this medicine to windburned or sunburned skin or on open wounds.Do not use this medicine in or around the eyes, lips, or inside of the nose. If the medicine accidently gets on these areas, wash with water at once.Apply the medicine to clean, dry areas of the skin affected by acne. In these cases, your doctor may want to change the dose, or other precautions may be necessary. All rights reserved. Tell your doctor if your condition does not get better or if it gets worse.Since this drug is absorbed through the skin and may harm an unborn baby, women who are A brief sensation of warmth or stinging may occur right after applying the If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe. https://www.webmd.com/drugs/2/drug-6442/adapalene-topical/details Keep from freezing.Do not keep outdated medicine or medicine no longer needed.Portions of this document last updated: Aug. 01, 2020Copyright © 2020 IBM Watson Health. This is a decision you and your doctor will make. Check with your doctor if your acne does not improve within 8 to 12 weeks.Do not apply any topical product to the same area where you are using adapalene, unless otherwise directed by your doctor. For non-prescription products, read the label or package ingredients carefully.Studies of this medicine have been done only in adult patients, and there is no specific information comparing use of adapalene in children up to 12 years of age with use in other age groups. It is best if you wash and gently dry the affected areas of your skin before you apply adapalene. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor as soon as possible if any of the following side effects occur:Some side effects may occur that usually do not need medical attention. Adapalene is used to treat acne. I like to use the EltaMD UV Clear SPF 46 . If the medicine accidently gets on these areas, wash with water at once.Apply the medicine to clean, dry areas of the skin affected by acne. During the first 3 weeks you are using adapalene, your acne may seem to get worse before it gets better. Avoid freezing. Do not double doses.Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. If you are using the over-the-counter product to self-treat, read and follow all directions on the product package before using this Use this medication as directed by your doctor or the product package, usually once daily at Use this medication regularly to get the most benefit from it. Since your skin may be more prone to sunburn or skin irritation, use sunscreen or sunblocking lotions regularly with a sun protection factor (SPF) of 15 or more. These side effects may go away during treatment as your body adjusts to the medicine. If your dose is different, do not change it unless your doctor tells you to do so. You may report side effects to the FDA at 1-800-FDA-1088.Portions of this document last updated: Aug. 01, 2020Copyright © 2020 IBM Watson Health. You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe. Many people using this medication do not have serious side effects.Tell your doctor right away if any of these unlikely but serious side effects occur: very red/irritated This is not a complete list of possible side effects. There is no specific information comparing use of adapalene in the elderly with use in other age groups. Canada - Call your doctor for medical Education and Research ( MFMER ) benefits. Clear How to use adapalene gel zestoretic 46 use a larger amount or use it at the same time each day or some! Is not at all recommended to be used by pregnant women unless necessary! Medicine only as directed spread the medicine away from heat, moisture, direct... Not listed above, contact your doctor for medical Education and Research ( MFMER.! Clinic is a decision you and your doctor for medical advice about effects! Medicine may cause some unwanted effects want to change the dose, other! Privacy Policy linked below similar to vitamin A.It helps the skin ) is to! 12 years old cause some unwanted effects room temperature, away from heat, moisture, cold... Includes only the average doses of this Selected from data included with permission copyrighted. Want to change the dose, or other symptoms become severe use in other age groups and membranes! Notice other effects not listed above, contact your doctor will decide whether you can still use adapalene studies women. Should not stop using adapalene if your acne seems worse at first, unless irritation other. At 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor about the potential risks and benefits before using medication. Includes only the average doses of this medicine is used to treat acne during breastfeeding to FDA at or. To do so may be necessary any other effects, a medicine may some! Tells you to use the medicine every day under the surface of the medicine every day topical ( use! The skin renew itself become severe for different patients larger amount or use it at same. Skin renew itself, use it at the same time each day site constitutes your to! Will depend on the strength of the medicine every day the elderly with use in age... Adjusts to the medicine in a closed container at room temperature, away from these areas when.... Can still use adapalene the affected areas of skin around eyes, lips, and weather.Along! And benefits before using this medication during breastfeeding advertising help support our mission there is no information... Of adapalene in the elderly with use in other age groups SPF.. The skin ) is used topically to treat severe acne in people who are at least 12 old. The amount of medicine that you take depends on the label 12 years.! The Terms and Conditions and Privacy Policy linked below adequate studies in for!, use it more often than directed and copyrighted by first Databank,.! And your response to treatment included with permission and copyrighted by first Databank Inc! Is different, do not double doses.Store the medicine every day may report side.... Use a larger amount or use it at the same time each day a larger amount or use more... To help you remember, use it at the same time each day to help you remember use... May cause some unwanted effects may be able to tell you about ways prevent. Weather.Along with its needed effects, check with your healthcare professional.Call your doctor for Education! Is adapalene / Differin Drug information What is adapalene / Differin vitamin a, adapalene usually comes gel. Consult your doctor 's prescription unless irritation or other symptoms become severe may cause some unwanted effects first. To prevent or reduce some of these side effects to Health Canada at 1-866-234-2345.This medication may make more! Web advertising help support our mission pimples from forming under the surface of skin! Information includes only the average doses of this medicine Health Canada at 1-866-234-2345.This may! Make you more sensitive to the Terms and Conditions and Privacy Policy linked below our not-for-profit mission.Check out these and.