Her best-corrected distance visual acuity was “count fingers” at 150 cm in both eyes, and her corrected near visual acuity was 20/200. 2. Garrabou G, Soriano A, Lopez S, et al. By Mayo Clinic Staff The most commonly reported side effects included diarrhea, dyspepsia, gastritis, nausea, and vomiting. 5, 6th Fl., 1400 Pelham Parkway South, Bronx, NY 10461 ( Diarrhea 2. "Possibly linezolid-induced peripheral and central neurotoxicity: report of four cases." Abena PA, Mathieux VG, Scheiff JM, Michaux LM, Vandercam BC "Linezolid and reversible myelosuppression." Cerner Multum, Inc. "Australian Product Information." Nutritional deficiencies can also result in toxic optic neuropathies, with vitamin deficiencies—in particular, of the B complex vitamins and folic acid—being the most crucial. We comply with the HONcode standard for trustworthy health information - Arellano FM "Linezolid and reversible myelosuppression." You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. JAMA 286 (2001): 1973-4; discussion 197446. John CC, Schreiber JR "Therapies and Vaccines for Emerging Bacterial Infections: Learning from Methicillin-resistant Staphylococcus aureus." Ann Pharmacother 37 (2003): 526-52947. The most important area of the retina is the macula, an area packed with photoreceptors whose axons form the most important bundle of fibers—the papillomacular bundle—entering the optic nerve. Elsie Lee, Susanne Burger, Christine Melton, Michael Mullen, Floyd Warren, Robert Press, Linezolid-Associated Toxic Optic Neuropathy: A Report of 2 Cases, We describe 2 cases in which the prolonged use of linezolid to treat complicated methicillin-resistant Toxic optic neuropathy is characterized by bilateral and symmetrical acute vision loss, central or cecocentral scotomas, and impaired color vision. Her vision progressively worsened during the following 2 weeks. Am J Ophthalmol 139 (2005): 1114-663. Clin Infect Dis 35 (2002): 347-840. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. A dilated fundus examination showed mild hypertensive retinopathy, and her optic nerves were pale temporally. Our Zyvox Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Early after onset, the optic nerves may appear to be normal, with later development of disc edema and hyperemia. Kohno S, Yamaguchi K, Aikawa N, et al. Linezolid also belongs to a class of drugs known as monoamine oxidase (MAO) inhibitors. Detroit, Michigan After receiving linezolid therapy for ∼10 months without myelosuppression and with no evidence of adverse side effects during monthly evaluations, patient 1 woke up one morning with acutely blurred vision. The bilateral visual field defects improved, and she regained some color vision in both eyes. Meyer B, Thalhammer F "Linezolid and continuous venovenous hemofiltration." Summary: We compare the side effects and drug effectiveness of Linezolid and Keflex. Kuter DJ, Tillotson GS "Hematologic effects of antimicrobials: focus on the oxazolidinone linezolid." infections (October)." You may report side effects to FDA at 1-800-FDA-1088. Clin Ther 28 (2006): 1155-6319. Association between the risk for cardiovascular events and antiviral treatment for herpes zoster He subsequently had transient subjective worsening of his vision, and successive MRIs revealed questionable transient occipital changes of undetermined significance that resolved over a period of a few days.Approximately 3 weeks after the discontinuation of linezolid treatment, his visual acuity improved to 20/30 in the right eye and to 20/40 in the left eye.