Knowledge about dose response is limited in both schizophrenia and bipolar disorder. Do not eat or drink for 10 minutes.
This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. Asenapine is ineffective if swallowed (bioavailability as a tablet formulation was < 2%).Asenapine is indicated for schizophrenia in adults. This system is called 'scheduling'.You can read more about the scheduling of medicines as well as the different scheduling categories on our For schizophrenia the starting dose is asenapine 5 mg twice daily.
However, most participants in monotherapy trials for bipolar I disorder continued on asenapine 10 mg twice daily.The safety and efficacy of doses above 10 mg twice daily has not been evaluated, and the efficacy of doses below 5 mg twice daily was not demonstrated for either condition.No dose adjustment is required for people who have mild to moderate hepatic impairment (Child–Pugh A or B).Asenapine is highly bound to plasma protein, and a study in healthy volunteers found no detectable renal elimination of unmetabolised asenapine. SAPHRIS is available as 5 mg and 10 mg wafers containing 5 mg asenapine (7.03 mg asenapine maleate) and 10 mg asenapine (14.06 mg asenapine maleate), respectively.
Warn patients to expect tingling or numbing of the tongue and mouth Asenapine wafers often have a local anaesthetic effect. Consider an alternative antidepressant or coadminister these with caution. If you are suffering an acute illness, overdose, or emergency condition, call triple zero (000) and ask for an ambulance.Reasonable care has been taken to provide accurate information at the time of creation.
It contains detailed, illustrated instructions for taking asenapine wafers. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk. Medicines with a low safety risk are usually less tightly controlled than medicines with a higher safety risk.
Clozapine is the first choice for treatment resistant schizophrenia. During the COVID-19 pandemic, you need to continue to take your usual medicines and stay as healthy as possible.
Our information hub has important information for everyone.Find out more about COVID-19 and the virus that causes it. Please discuss your individual circumstances with your pharmacist, doctor or health professional. They can help you balance the risks and the benefits of this medicine during pregnancy.You can help ensure medicines are safe by reporting the side effects you experience.You can report side effects to your doctor, or directly at The way to take this medicine is: Sublingual.