Indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitusMay be dosed 2, 3, or 4 times a day in response to changes in meal patternSerious CV events (4%; versus 3% incidence with glyburide and glipizide)Coadministration of gemfibrozil results in increased repaglinide plasma concentration (8-fold increase); may lead to severe hypoglycemiaStress due to infection, fever, trauma, or surgery; may need to discontinue if exposed to stressPatients at risk of severe hypoglycemia: Elderly, debilitated, or malnourished; adrenal or pituitary insufficiencyMyocardial ischemia reported in patients treated concomitantly with NPH-insulin; not indicated for use in combination with NPH-insulinThe use of sulfonylureas may be associated with increased cardiovascular eventsDrugs that inhibit organic anion transporting protein OATP1B1 (eg, cyclosporine) may increase plasma concentrations of repaglinide, which is a substrate for active hepatic uptake transporter OATP1B1Limited available data from case reports and case series have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal, or fetal outcomes in women taking repaglinide while pregnantDetected in breast milk of rat dams and lowered blood glucose levels were observed in the pupsCross fostering studies indicated that skeletal changes could be induced in control pups nursed by treated dams, although this occurred to a lesser degree than those pups treated in uteroA: Generally acceptable. clinical recovery.
Please check with a physician if you have health questions or concerns. Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl)
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× Interactions. Cyclosporine and cyclosporine (modified) are used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants. NIDDM).
]Protect from light.Dispense in a tight, light-resistant container as defined in the USP using a
Most commonly, these are "preferred" (on formulary) brand drugs. hemodialysis.Store at 20° to 25°C (68° to 77°F). Prandin (repaglinide) is an oral diabetes medicine that helps control blood sugar levels by causing the pancreas to produce insulin.Prandin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.. Prandin is not for treating type 1 diabetes.. If you skip a meal, do not take your dose of Prandin. Hypoglycemic symptoms without loss of consciousness or neurologic findings
child-resistant closure.PHARMACIST:Store at 20° to 25°C (68° to 77°F).
]Protect from light.Dispense in a tight, light-resistant container as defined in the USP using a Visit cvs.com for more details.
Description and Brand Names.
4: This drug is available at a higher level co-pay. 117853-overview
are allergic to cyclosporine (brand name Restasis) are wearing contact lenses. People with type 1 diabetes are unable to produce any insulin, even if they take medications. Changing any of these factors can affect your blood sugar levels.You should not use Prandin if you are allergic to repaglinide, or if you have:diabetic ketoacidosis (call your doctor for treatment).Many drugs can interact with repaglinide and some drugs should not be used at the same time. You may report side effects to FDA at 1-800-FDA-1088.Many other medicines that can increase or decrease the effects of repaglinide on lowering your blood sugar.
]Protect from light.Dispense in a tight, light-resistant container as defined in the USP using a
Cyclosporine (modified) is also used alone or with methotrexate (Rheumatrex) to treat the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints) in patients whose symptoms were not relieved by methotrexate alone. Your list will be saved and can be edited at any time.The above information is provided for general Cyclospor… Follow your doctor's instructions. Controlled studies in pregnant women show no evidence of fetal risk.Increases insulin secretion by blocking ATP potassium channels on beta islet cells, which facilitates calcium entry through calcium channels; increased intracellular calcium stimulates insulin release from pancreatic beta cellsMetabolized extensively in liver, by CYP3A4 and CYP2C8Metabolites: Oxidized dicarboxylic acid, aromatic amine, acyl glucuronide (inactive)May be dosed 2, 3, or 4 times a day in response to changes in meal patternSkipped meals: Instruct patients to skip the scheduled repaglinide dose to reduce the risk of hypoglycemiaAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans.