Pindolol and thioridazine
Propranolol and thioridazine should not be co-administered.Concurrent administration of pindolol and thioridazine have resulted in moderate,
Thioridazine may also be used for purposes not listed in this medication guide. Follow all instructions closely. Thioridazine is used to treat schizophrenia. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
thioridazine has been shown to prolong the qtc interval in a dose related manner, and drugs with this potential, including thioridazine, have been associated with torsade de pointes-type arrhythmias and sudden death. Combining these medications can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.
Inhaltsverzeichnis. Thioridazine is usually given after other antipsychotic medicines have been tried without success.
Severe respiratory depression and respiratory arrest have been reported when a patient was given a phenothiazine and a concomitant high dose of a barbiturate.Where patients are participating in activities requiring complete mental alertness (e.g., driving) it is advisable to administer the phenothiazines cautiously and to increase the dosage gradually. The drug's name is derived from the methylsulfoxy and piperidine functional groups in its chemical structure. What are the possible side effects of thioridazine (Mellaril)? Brand names: Mellaril, Mellaril-S Drug class(es): phenothiazine antipsychotics Thioridazine systemic is used in the treatment of: Schizophrenia Female patients appear to have a greater tendency to Antipsychotic drugs elevate prolactin levels; the elevation persists during
Tissue culture experiments indicate that approximately
(e.g., fluoxetine and paroxetine), and certain other drugs (e.g., fluvoxamine,
It also improves learning …
manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status,
for one week) on thioridazine steady state concentration was evaluated in 10 male in-patients with Concurrent administration of propranolol (100 to 800 mg daily) has been reported to produce increases in plasma levels of thioridazine (approximately 50% to 400%) and its metabolites (approximately 80% to 300%). To view the price of the drug, click on the brand name. the Thioridazine use should be avoided in combination with other drugs that are
Thioridazine is usually given after other antipsychotic medicines have been tried without success. Medindia's drug directory has currently 46 Brands of Thioridazine listed.
Do not take two doses at one time.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Avoid driving or hazardous activity until you know how thioridazine will affect you.
that prolong the QTc interval. There is no general
CONSEQUENTLY, BEFORE INITIATING TREATMENT WITH THIORIDAZINE, IT IS STRONGLY RECOMMENDED THAT A PATIENT BE GIVEN AT LEAST TWO TRIALS, EACH WITH A DIFFERENT ANTIPSYCHOTIC DRUG PRODUCT, AT AN ADEQUATE DOSE, AND FOR AN ADEQUATE DURATION. as well as in patients, comprising about 7% of the normal population, who are
Brand Names: Mellaril Generic Name: thioridazine. defect leading to reduced levels of activity of P450 2D6 (see The basic pharmacological activity of thioridazine is similar to that of other phenothiazines, but is associated with minimal extrapyramidal stimulation.However, thioridazine has been shown to prolong the QTc interval in a dose-dependent
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clinical detection, please refer to the sections on It has been suggested in regard to phenothiazines in general, that people who have demonstrated a hypersensitivity reaction (e.g., blood dyscrasias, jaundice) to one may be more prone to demonstrate a reaction to others.
Thioridazine is used to treat schizophrenia. Therefore, the co-administration of drugs that inhibit P450 2D6 with thioridazine and the use of thioridazine in patients known to have reduced activity of P450 2D6 are contraindicated.The effect of fluvoxamine (25 mg b.i.d. firmly established. Adequate In managing overdosage, the physician should always consider the possibility
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