Common side effects include nausea, diarrhea… It is taken either by mouth or injection into a vein.. Side effects are rare. Applies to tranexamic acid: compounding powder, intravenous solution, oral tablet. "Product Information. Along with its needed effects, tranexamic acid may cause some unwanted effects. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. ➡️In patients with acquired defective color vision, since this prohibits measuring one endpoint that should be followed as a measure of toxicity.➡️In patients with subarachnoid hemorrhage, anecdotal experience indicates that cerebral edema and cerebral infarction may be caused by tranexamic acid injection in such patients.➡️In patients with hypersensitivity to tranexamic acid or any of the ingredients. Single dose: Mean: 2.5 hours (range: 1 to 5 hours).Multiple dose: Mean: 2.5 hours (range: 2 to 3.5 hours).Following administration of a single IV injection, urinary excretion declines as renal function decreases.In vitro data suggests that neonates require a lower serum tranexamic acid concentration than adults (6.54 mcg/mL vs 17.5 mcg/mL) to completely prevent fibrinolysis (Yee 2013). Nervous system side effects have included giddiness, dizziness, headache, tension headache, and migraine. It is present in the mother’s milk at a concentration of about a hundredth of the corresponding serum levels. Some experts recommend 1 g, followed by 1 g over 8 hours as a continuous infusion, for no more than 36 hours (Post 2019).IV: 10 mg/kg using actual body weight (usual dose range: 500 mg to 1 g) administered ~2 hours before procedure at a rate not to exceed 100 mg/minute (generally over 10 to 20 minutes), then 10 mg/kg 3 to 4 times daily for 2 to 8 days. Freezing tranexamic acid in original vials has not been evaluated.Premixed solution: Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).Tablets: Store at 25°C (77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).Anti-inhibitor Coagulant Complex (Human): Antifibrinolytic Agents may enhance the thrombogenic effect of Anti-inhibitor Coagulant Complex (Human). These side effects are life-threatening.If tranexamic acid doesn’t work for you, or if the side effects are bothersome, your doctor may suggest alternative medications for heavy periods. Administer immediately after preparation.Inhalation via nebulization (off-label use/route): Administer over 15 minutes via jet nebulizer (Segrelles 2016; Wand 2018).Injection: May be administered by direct IV injection at a maximum rate of 100 mg/minute (Crash-trial collaborators 2010; Elwatidy 2008; WOMAN Trial Collaborators 2017); faster rates may cause hypotension.Oral: Administer without regard to meals. Total blood loss, number of transfusions required, and units of blood transfused were significantly reduced, and hematological indices were significantly improved with administration of tranexamic acid Data from numerous prospective, blinded, randomized, controlled trials that were analyzed in a meta-analysis support the use of tranexamic acid to reduce blood loss and the need for transfusions during spinal surgery Data from a large international, randomized, double-blind, placebo-controlled trial evaluating the early administration of IV tranexamic acid in women (≥16 years of age) with postpartum hemorrhage following vaginal birth or cesarean delivery support the use of tranexamic acid for treatment of postpartum hemorrhage. According to Robinson, tranexamic acid "is compatible with many other skincare ingredients." 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