It involves drinking a bottle of water before bed along with a couple ibuprofen. And take it in the morning with water and some breakfast.As long as she isn't taking a huge amount of ibuporfen that's generally considered fine. (3 × 200mg ibuprofen) + 10 shots sounds like a horrible ordeal for the stomach if this is a regular occurrence.It is bad for your liver. And yeah, most hangover symptoms are caused by dehydration (and electrolyte imbalances in some cases).Change it to aspirin instead. Way safer. One study of 1,224 participants showed that regular use of ibuprofen raised the risk of stomach and intestinal bleeding in people who consumed alcohol. The more alcohol that a person drinks, the harder the kidneys have to work.Ibuprofen and other NSAIDs affect kidney function because they stop the production of an enzyme in the kidneys called cyclooxygenase (COX). Aspirin and naproxen are NSAIDs, which means that they belong to the same class of medication as ibuprofen and carry many of the same risks.Natural remedies are not necessarily any safer to take with alcohol. Mixing the two further increases the risk of ulcers and bleeding.The risk of stomach ulcer bleeding increases the longer a person takes ibuprofen. MNT is the registered trade mark of Healthline Media. You're thinking of APAP.Ibuprofen doesn't damage the liver like acetaminophen (Tylenol/APAP) does. Press question mark to learn the rest of the keyboard shortcutsCookies help us deliver our Services. My girlfriend gets really bad hangovers when she drinks but thinks she's found a fail proof hangover cure. Some herbal medicines and natural supplements can also interact with alcohol and cause side effects.When someone has already had more than a moderate amount of alcohol, the safest approach to pain relief is to wait until the alcohol is out of the body before taking ibuprofen or other pain medicines.A person can relieve pain using other methods, including:While people can typically have a small amount of alcohol with ibuprofen, the safest option is to avoid mixing the two.People who have health conditions should talk with a doctor about their medications and alcohol consumption to determine what is safe for them.What should I do if I have taken alcohol and ibuprofen together?If you have consumed a small-to-moderate amount of alcohol along with ibuprofen, do not drink any more alcohol. Making sure you're hydrated before bed is a definite hangover cure though.When drunk, if I don't take an ibuprofen before bed, I almost often wake up three hours later with an anvil-grade headache.But everybody being different, it's just my own experience :)Exactly. People can also use different types of pain reliever or alternative pain relief methods.However, other pain medications, such as acetaminophen (Tylenol), naproxen (Aleve), and Acetaminophen affects the liver and can cause life-threatening liver damage in people who drink alcohol regularly. Additionally, we should expect synergistic stomach-irritation when it is taken in such proximity to alcohol.Honestly, 9-10 shots would give nearly anyone a nasty hangover that's difficult to 'cure'.New comments cannot be posted and votes cannot be castSourcing drugs is NOT allowed here! In this article, we discuss the risks of mixing alcohol and ibuprofen. In the future, you should avoid taking any pain reliever with alcohol.© 2004-2020 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. I'm concerned having that and alcohol in her system might be worse for the liver than alcohol alone. It's likely a total placebo. All rights reserved. However, she eventually realised that the ibuprofen really wasn't doing anything and in fact two big glasses of water before bed was a much more effective hangover prevention.Meanwhile when I was a dumb teenager, I used to take ibuprofen BEFORE drinking in order to get drunk easier...Ibuprofen has a comparatively short half-life, so there's no real point to taking it directly before bed. When a person takes ibuprofen for an extended period or in high doses, it can increase their risk of gastric ulcers or bleeding in the digestive tract.Alcohol can also irritate the stomach and digestive tract. 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