Triamterene on the other hand, is a weaker diuretic that causes potassium to be retained in the body. In rare instances, this edema may cause extreme discomfort which is not relieved by rest. home Prednisolone. Cationic exchange resins such as sodium polystyrene sulfonate may be orally or rectally administered. All patients changed from less bioavailable formulations to Triamterene and Hydrochlorothiazide tablets should be monitored clinically and for serum potassium after the transfer.Triamterene and Hydrochlorothiazide Tablets, USP, 37.5 mg/25 mg, are light green, round, scored tablets, debossed with Triamterene and Hydrochlorothiazide Tablets, USP, 75 mg/50 mg, are yellow, round, scored tablets, debossed with Bottles of 100 tablets are provided with child-resistant closures.Store at 20° to 25°C (68° to 77°F) [See USP Controlled Room Temperature]. triamterene 75 mg-hydrochlorothiazide 50 mg tablet. There is hypervolemia during normal pregnancy which is harmful to neither the fetus nor the mother (in the absence of cardiovascular disease), but which is associated with edema, including generalized edema, in the majority of pregnant women. Protect from light.Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Although hepatocellular neoplasia (exclusively adenomas) in the rat study was limited to triamterene-exposed males, incidence was not dose-dependent and there was no statistically significant difference from control incidence at any dose level.The safe use of Triamterene and Hydrochlorothiazide tablets in pregnancy has not been established since there are no adequate and well-controlled studies with Triamterene and Hydrochlorothiazide tablets in pregnant women. Triamterene is 2, 4, 7-triamino-6-phenylpteridine. Each Triamterene and Hydrochlorothiazide tablet, 75 mg/50 mg, contains triamterene, USP, 75 mg and hydrochlorothiazide, USP, 50 mg. Each triamterene and hydrochlorothaizide tablet, 37.5 mg/25 mg, contains triamterene, USP, 37.5 mg and hydrochlorothiazide, USP, 25 mg.Both strengths of Triamterene and Hydrochlorothiazide tablets for oral administration contain the following inactive ingredients: anhydrous lactose, microcrystalline cellulose, polacrilin potassium, polyethylene glycol 8000, povidone, and magnesium stearate. it is usually taken once daily, with or without food. Any chloride deficit during thiazide therapy is generally mild and usually does not require any specific treatment except under extraordinary circumstances (as in liver disease or renal disease). This fixed combination drug is not indicated for the initial therapy of edema or hypertension except in individuals in whom the development of hypokalemia cannot be risked.Hyperkalemia: Abnormal elevation of serum potassium levels (greater than or equal to 5.5 mEq/liter) can occur with all potassium-conserving diuretic combinations, including Triamterene and Hydrochlorothiazide. If this medicine is taken with other medicines that can increase blood potassium levels, this effect may be enhanced. If hyperkalemia develops, this drug should be discontinued and a thiazide alone should be substituted. Triamterene is primarily metabolized to the sulfate conjugate of hydroxytriamterene. Serum potassium should be monitored frequently.Triamterene and quinidine have similar fluorescence spectra; thus, Triamterene and Hydrochlorothiazide may interfere with the measurement of quinidine.There was an increased incidence of hepatocellular neoplasia (primarily adenomas) in male and female mice at the highest dosage level.