Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions.
Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS). Amlodipine 2.5 mg is not currently available and the 2.5 mg dose cannot be obtained with Amlodipine tablets 5 mg and 10 mg as these tablets are not manufactured to break into two equal halves. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Take this medicine only as directed by your doctor. Follow your doctor's orders or the directions on the label. Your doctor will tell you which of these are most important for you.
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Drugs
Use in children and adolescents (6 -17 years old) The recommended usual starting dose is … In adults, the initial dose is 1000 mg of DURICEF and the maintenance dose (based on the creatinine clearance rate [mL/min/1.73 M 2 ]) is 500 mg at the time intervals listed below.
infusion (2.5, 5.0, or 10.0 mg).
Available for Android and iOS devices. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Amlodipine / atorvastatin systemic 2.5 mg / 10 mg (CDT 251) Indicated for hypertension, to lower blood pressureLowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions5 mg/day PO initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day maintenance: 5-10 mg/dayTreatment of chronic stable angina, vasospastic angina (Prinzmetal or variant angina), and angiographically documented CAD in patients without heart failure or EF <40%5-10 mg/day PO initially; maintenance: 10 mg/day POStart dosing at low end of dosing range; elderly patients have greater frequency of decreased renal, hepatic or cardiac function2.5-5 mg/day PO initially; may be increased by 2.5 mg/day every 7-14 days; not to exceed 10 mg/day PO; maintenance: 5-10 mg/day POTreatment of chronic stable angina, vasospastic angina (Prinzmetal or variant angina), and angiographically documented CAD in patients without heart failure or EF <40%2.5-10 mg/day PO initially; maintenance: 10 mg/day POCardiovascular: Arrhythmia (eg, ventricular tachycardia, atrial fibrillation), bradycardia, chest pain, peripheral ischemia, syncope, tachycardia, vasculitisCentral and peripheral nervous system: Hypoesthesia, neuropathy peripheral, paresthesia, tremor, vertigoGastrointestinal: Anorexia, constipation, dysphagia, diarrhea, flatulence, pancreatitis, vomiting, gingival hyperplasiaGeneral: Allergic reaction, asthenia, back pain, hot flushes, malaise, pain, rigors, weight gain, weight decreaseMusculoskeletal system: Arthralgia, arthrosis, muscle cramps, myalgiaPsychiatric: Sexual dysfunction (male and female), insomnia, nervousness, depression, abnormal dreams, anxiety, depersonalizationSkin and appendages: Angioedema, erythema multiforme, pruritus, rash, rash erythematous, rash maculopapularSpecial senses: Abnormal vision, conjunctivitis, diplopia, eye pain, tinnitusUrinary system: Micturition frequency, micturition disorder, nocturiaAutonomic nervous system: Dry mouth, sweating increasedPulmonary edema (higher incidence in heart failure patients)Jaundice and hepatic enzyme elevations (mostly consistent with cholestasis or hepatitis)Symptomatic hypotension is possible, particularly with severe aortic stenosis; owing to gradual onset of action, acute hypotension unlikelyWorsening of angina and acute myocardial infarction (MI) can develop after dose is started or increased, particularly with severe obstructive CADExtensively metabolized by the liver and plasma elimination half-life is 56 hr in patients with hepatic impairment; titrate slowly when treating patients with severe hepatic impairmentLimited available data based on postmarketing reports are insufficient to inform a drug-associated risk for major birth defects and miscarriage during pregnancyLimited available data from a published clinical lactation study reports that amlodipine is present in human milk at an estimated median relative infant doseNo adverse effects of amlodipine on breastfed infant reportedThere is no available information on effects of amlodipine on milk productionA: Generally acceptable. Select one or more newsletters to continue.
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of this medicine, take it as soon as possible.