suggestive of liver dysfunction occur (e.g., nausea, vomiting, abdominal pain, fatigue, In clinical trials with CASODEX 150 mg as a single agent for A reduction in glucose tolerance has been observed in males receiving LHRH agonists. reliably estimate their frequency or establish a causal relationship to drug exposure.Clinical studies have not shown any drug interactions between bicalutamide and LHRH analogs
Co-administration of terfenadine, astemizole or cisapride with Casodex is contraindicated (see section 4.5). may be new information. 1681/19, 2nd Floor, Mangal Market Bhagirath Palace, Chandni Chowk, Delhi - 110006, Delhi Nagpur, Maharashtra References. 130, New Jagruti Colony, Katol Road, Nagpur - 440013, Dist. Do not give CASODEX to other people, even if
You can ask your healthcare provider or
Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. observed to have reduced anogenital distance, smaller secondary sex organs, CASODEX is not indicated for use in pregnant women. Figure 1). Limited data in subjects with severe hepatic
There were 294 (37.7%)
Apple Square, Gajera Circle, Near Gajera School, Katargam, 205 2nd Floor, Katargam, Surat - 395004, Dist. Risk of photosensitivity—avoid excessive exposure to UV light and sunlight. Therapy: … Bicalutamide 150 mg film-coated tablets. Mumbai, Maharashtra polyethylene glycol, polyvidone, sodium starch glycollate, and titanium dioxide.The recommended dose for CASODEX therapy in combination with an LHRH analog is one 50 mg tablet
dosages have been well tolerated. caused abnormal development of reproductive organs in male fetuses at exposures approximately 0.7 to 2
you.Some people have had skin sensitivity to sunlight while taking CASODEX. 4402, 5A7, Ground Floor, Ansari Road Opposite HDFC Bank, Daryaganj, New Delhi - 110002, Delhi In patients with
Periodic liver function tests should be considered for No clinically significant difference in the pharmacokinetics of either enantiomer of bicalutamide was
: +919924144744, Surat - 395004, Dist. monotherapy (CASODEX 150 mg daily is not approved for use as therapy for patients with localized prostate cancer
For more information, ask your healthcare provider or
263/264, Shop No. For more information go to
offspring leading to CASODEX is contraindicated for use in pregnant women because it can cause fetal harm. their healthcare provider [see Inform patients that CASODEX can cause hepatitis, which may result in hepatic failure and
Nagpur, Maharashtra of the tablet’s components. In addition, the clinical benefit of bicalutamide 150 mg in locally advanced patients, but not in those with localized disease, is consistent with the overall results from the EPC program (McLeod et al. each body system regardless of causality.Laboratory abnormalities including: elevated AST, ALT, bilirubin, BUN, and creatinine; and decreased
during treatment. CASODEX treatment be discontinued in the M1 patients because the risk of death was 25% (HR 1.25,
Hypersensitivity reactions including angioneurotic edema and CASODEX has no indication for women, and should not be used in this population.CASODEX can cause fetal harm when administered to a pregnant woman [see In a subset of patients who have been treated with CASODEX and an Bicalutamide is well-absorbed following oral administration, although the absolute bioavailability is
22 and allowed to litter and rear their offspring to weaning. Bicalutamide has a molecular weight of 430.37. Serum transaminase levels should be measured prior to starting treatment with CASODEX, at regular
cancer are presented in Table 3.In a multi-center, double-blind, controlled clinical trial, 813 patients with previously untreated advanced
Unit No. Hepatotoxicity in these reports generally
Bicalutamide has been detected in rat milk.Antiandrogen therapy may cause morphological changes in spermatozoa [see Based on animal studies, CASODEX can lead to inhibition of The safety and effectiveness of CASODEX in pediatric patients have not been established.CASODEX (bicalutamide) orodispersible tablet was studied in combination with The starting CASODEX dose was 12.5 mg. CASODEX was titrated in each patient until steady-state
These are three
pharmacist for information about CASODEX that is written for health professionals. BJU Int 97:247–254, 2006). Nagpur, Maharashtra which is the range of therapeutic concentrations achieved in adults with The primary efficacy analysis of the study was to assess the change in growth rate after 12 months of
Advise patients that liver function tests should be monitored regularly during treatment and to
1.6 cm/year, 95% CI (-4.7 to 1.5) p=0.28; the mean growth rate SDS decreased by 0.1 SD, 95% CI (–1.2
report signs and symptoms of hepatitis [see Inform patients that diabetes or loss of glycemic control in patients with pre-existing
use CASODEX for a condition for which it was not prescribed. impairment suggest that excretion of CASODEX may be delayed and could lead to further accumulation. 3rd Floor, Block A, Shree SSD Heights, Ganjipeth, Nagpur - 440018, Dist. Shop No. Casodex may also be used for purposes not listed in this medication guideBicalutamide blocks the effect of the natural male hormones on the growth of prostate cells. 12/B, 2nd Floor, Thacker Industrial Estate N. M. Joshi Marg, Parel, Mumbai - 400011, Dist.