For instance, grade 4 contains increasingly abnormal and rapid growth cancer cells that are more likely to recur; ■ Lymph nodes – inflammation of lymph nodes is indicative of higher risk; ■ Lymphatic or vascular invasion – presence o… For example, a woman age 40-45 at diagnosis with an estrogen positive (ER +) receptor has a 4.8% chance of getting a contralateral cancer in her opposite breast within 20 years of her diagnosis. The risk factors accounted for in this breast cancer recurrence calculator are: ■ Grade of tumor – the higher the grade, the more likely a recurrence is. Read our Get in touch with MDApp by using the following contact details: Local recurrence. Risk of breast cancer recurrence . Fill in the calculator/tool with your values and/or your answer choices and press Calculate.Please note that once you have closed the PDF you need to click on the Calculate button before you try opening it again, otherwise the input and/or results may not appear in the pdf.This calculator evaluates recurrence risk in the case of patients suffering from breast cancer or metastatic disease.The three risk factors found to have predictive value are:The higher the grade of breast tumor, the higher the risk of recurrence because the cells are more prone to subsequent activation and proliferation.Lymphatic or vascular invasion refers to the presence of breast cancer cells in the lymphatic or vascular system.■ At the original site (breast, chest or lymph nodes in the armpit);■ Metastasis or distant recurrence (most common in the bones, liver or lungs).The first five years after treatment are the years with the highest recurrence risk (11%). This health tool evaluates recurrence risk in the case of patients with a recurrence of breast cancer or metastatic disease. Lifestyle changes may also help, such as healthy dieting, regular exercise and no excessive drinking.In order to increase chances of rapid diagnostic and intervention, breast cancer survivors are recommended regular mammograms, preferably 3D in addition to the traditional digital ones.O'Rourke S, Galea MH, Morgan D, Euhus D, Pinder S, Ellis IO, Elston CW, Blamey RW. The outcome was the following:■ 223 developed local recurrence (appx 50% of cases were small single lesions);■ 21 developed diffuse carcinomatous dermal infiltration.In the case of women scoring high, adjuvant irradiation should be recommended to decrease the likelihood of malignancy recurrence.Beside lymph node involvement and tumor histologic grade, there are other prognostic indicators such as:■ Hormone receptors – significant levels of estrogen receptors;A local recurrence may be suspected following changes in the size, shape or contour of the breast along with changes in the feel or appearance of the breast or nipple.In some cases, the skin may be dimpled, red or swollen. (1994) 4) Christiansen P, Al-Suliman N, Bjerre K, Moller S; Danish Breast Cancer Cooperative Group. An online prognostic tool accurately determined the risk for late distant recurrence among women with ER-positive breast cancer, according to a single … A breast cancer recurrence happens when the same cancer comes back in the same breast (local recurrence) or in nearby lymph nodes (regional recurrence).Your estrogen receptor, just like your age at diagnosis, plays a big role in your risk of getting a contralateral breast cancer.