Benadryl is generally well tolerated but can cause the following side effects: As mentioned above, the combination of Benadryl and Zantac is considered safe. save hide report. It is not uncommon to use Benadryl for allergy symptoms or to treat insomnia and take Zantac for unrelated stomach symptoms. While classified as a antihistamine, Zantac, as well as other H2 blockers, differ from the antihistamines used for allergies like Benadryl and Claritin, which block histamine at the H1 receptor. I have noticed that as long as I take 2 of them (150mg), that it will make me a little less reactive. Is it OK to take Mucinex DM and Delsym together? Drugs that affect hormone levels can cause true acne. This thread is archived. New comments cannot … He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. Would Thrive W capsules affect my birth control, Microgestin? Now I'm thinking to try another H2 antihistamine called ranitidine. Since we know that acne is caused by inflammation, and allergies cause inflammation, is there a possible link between taking an antihistamine and a reduction in acne? While classified as a antihistamine, Zantac, as well as other H2 blockers, differ from the antihistamines used for allergies like Benadryl and Claritin, which block histamine at the H1 receptor. While doctors don’t know the exact cause of acne, one important factor is an increase in male sex hormones called androgens. Granted, I still have to watch myself and I can still have an attack for sure. In fact, both have been used together for the treatment of hives. Certain medications, especially those that affect your hormones, can also cause acne. H2 blockers: You may be told to take more than one type of antihistamine at a time for your hives. 9 comments. 64% Upvoted. I was already on PPIs for three months and am terrified when it comes to long-term side effects... H2 antihistamines seem safer - I did not think them to be ototoxic and had no tinnitus listed as side effect. share. But OTC acne and anti-aging products with retinol can cause dryness, peeling, and sun sensitivity as well. Benadryl begins to work about 20 to 30 minutes after taking by mouth and maximum blood concentrations are reached after 1 to 2 hours. In our latest question and answer, the pharmacist discusses whether or not there is an interaction between Benadryl and Zantac (ranitidine).Benadryl (diphenhydramine) and Zantac (ranitidine) can safely be taken together. For medical care, consult a medical professional.Similar Threads - Antihistamines (Famotidine Ranitidine) Many acne suffer from adult acne naturally can contain various chemicals to kill the bacteria that acne will periods; You can however modify and control it before they develop the skin; This type of acne (acne scar cream and are used as cystic acne can result in deep and it is … Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. Information published on this site is not intended as a substitute for medical advice. H2 blockers work to reduce acid production by blocking parietal cells from being stimulated to produce acid by histamine. H2 blocking antihistamines are indicated for the treatment of many conditions resulting from increased acid production in the stomach including: Although H2 blockers are generally used for stomach related issues, evidence suggests they are also beneficial for treating hives.Benadryl (diphenhydramine) is a first generation antihistamine, which are noted for their relatively short duration of action (~4 to 8 hours) and their sedating properties. Zantac (Ranitidine) Zantac (ranitidine) is classified as a H2 blocker and works by blocking histamine at the H2 receptor. Products with salicylic acid and benzoyl peroxide can also increase your vulnerability. Because it can make you drowsy, your doctor will probably tell you to take it at night. One type acne of vitamin A-derived medication, isotretinoin (Accutane) and tretinoin (Retin-A) can cause hair loss. The duration of action varies by individual but generally lasts 4 to 6 hours.