Flonase is a class c though so you … Claritin is an antihistamine and Flonase is a corticosteroid. Benadryl causes sedation and drowsiness for a short period of time, which is one of the properties of a “first-generation” antihistamine whereas Claritin’s effect lasts for 24 hours for one dosage and does not cause sedation which are the properties of a “second-generation” antihistamine.Due to the different and contrasting characteristics of both Benadryl and Claritin, they are usually not recommended to be taken together. In our latest question and answer, the pharmacist discusses whether or not nasal steroids such as Flonase can be combined with antihistamines like Benadryl.Can I take the nasal steroid Flonase (fluticasone) and Benadryl (diphenhydramine) together for runny nose and watery eyes?Yes, Flonase (fluticasone nasal spray) can be used safely with Benadryl (diphenhydramine). This can cause heart issues. I didnt see and answer here so I just called Walgreens and spoke with a pharmacist. Intra-nas ... Why zyrtec if you already took claritin d ? Compare Benadryl vs Flonase head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Benadryl is known to cause sedation when taken and if it is combined with Claritin then the sedation can be pronounced even though Claritin is considered to be a non-sedative. It blocks the action of histamines that initiates allergic symptoms like runny nose, skin rashes, watery eyes, and sneezing.The most significant difference between Benadryl and Claritin is that Benadryl causes more sedation and drowsiness than Claritin. Flonase reduces inflammation and nasal symptoms associated with rhinitis; however, Flonase may cause nose bleeds and it takes about three days for the full effects to be seen. The chewable tablets can be chewed, followed by swallowing it. Prescribed for Allergic Rhinitis, Urticaria. How do I dry out the infected area? Subscribe to MedHelp's free newsletter for Community Support, Experience, and Guidance. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. They must be taken as per the doctor’s prescription or according to the instructions given in the labels. If you are particular benedryl atleast child can rest.They are both antihistamines but Benadryl (diphenhydramine) often causes drowsiness but is more effective in drying up the nose. We often wonder and look for answers about taking a combination of drugs together and it is always best to check and research well before taking drugs in combination. Flonase and Claritin CAN be taken together but make sure you read the directions for both and aren't taking any other medication that can counteract the effects of either medication. Taking combinations of antihistamines increases the possibility of side effects. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. Yes that is completely fine. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. I was informed that Flonase and Benadryl are fine to take together- there are no interactions. I take Zyrtec and Flonase daily and they did nothing. Also Flonase can cause serious problems for people who already have liver disease. Benadryl (diphenhydramine) is a first generation, sedating antihistamine that is often used for the treatment of allergy symptoms as well as insomnia. I have severe congestion and my Dr is letting me use flonase because benadryl doesn't help with congestion. I would avoid taking multiple antihistamines in the same day.All of these medicines are antihistamines. Claritin. Can I take my regular Claritin-D at 11 AM the morning after? Usage of the drugs must be strictly followed according to the dosage as prescribed by the doctor.Benadryl can be taken orally in the form of capsules, tablets, or liquid with or without food. If you could let me know I would greatl... Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Bezack on claritin d flonase benadryl: Both are antihistamine decongestant combinations and have similar mechanism of action. The rapidly-dissolving tablets must be kept on the tongue until it dissolves on its own and then swallowed.