(File photo)A review at the University of Genova concluded patients taking steadily-releasing anti-inflammatory drugs just before bedtime had less pain and stiffness in the morning than those who’d taken them when waking up.The over-reaction of the immune system that causes the disease, and release of inflammatory enzymes, accelerates at night and builds up until the early hours.Delivering drugs at night gradually releases the pills into the bloodstream, blocking the surge in inflammatory substances.A series of studies in the 1980s found that some non-steroidal anti-inflammatory medication, such as ibuprofen or naproxen, can be most effective when taken roughly eight hours before the most acute pain.Odours affect mood and behaviour in different ways due to a process called associative learning. An overdose of paracetamol can cause serious harm. Using more paracetamol could cause damage to your liver. This is one by which one item is psychologically associated with another due to past experiences. As the problem is often worse while eating, the scientists found patients reported less discomfort if the drug was taken before the evening meal.‘So it’s best to take it in the evening when levels are naturally low.’This theory has been demonstrated in several mice studies by researchers at the University of Wisconsin.‘If you give paracetamol to mice when they are most ”wakeful”, their liver levels of NAPQI are far higher over a 24 hour period, compared to when they are resting,’ says Dr Dallman.Paracetamol overdose is the cause of almost a third of liver transplants in the UK, according to The British Liver Trust.Dr Dallam says: ‘We produce most of our large blood cells, called platelets, during the night.‘This makes our blood thick and sticky, so by the morning it’s at its stickiest, making it much more likely to clot.‘As well as this, blood pressure peaks just before you get up, as does heart rate, preparing your body for wakefulness. Adults can usually take one or two 500mg of paracetamol tablets every 4-6 hours, but shouldn't take more than 4g - eight 500mg tablets - in the space of 24 hours. A fifth of Britons over 70 take a staggering seven pills daily.And with instruction lists as long as your arm, precisely what time of day you should take each one can be confusing. So you have thicker blood that is passed through the arteries at greater force.’Taking medications to prevent stroke and heart attacks at night prevents this chain reaction.Most rheumatoid arthritis sufferers find their pain and stiffness is far worse in the morning, making them reach for their pills which can take hours to yield relief. We are no longer accepting comments on this article.Part of the Daily Mail, The Mail on Sunday & Metro Media GroupTrump slams Biden for being controlled by 'crazy socialists' in the Democrat party and attacks Nevada Gov. As a result, some drugs are best given at night and others during the day.’The most common treatments for heartburn, or acid reflux, work by limiting the amount of acid produced by the stomach. I've taken paracetamol before early before giving blood (for a headache not to 'numb' any pain) and there was no problem. Taking amoxicillin for a digestive problem while you also have a headache can be pretty common so, in fact, the short answer is yes, you can take both at the same time. If you're having a blood test to check whether your medicine is working, in most cases you should keep taking your medicine. And don’t wait until after dinner. You should never stop taking prescribed medicine, unless you're told to do so by your doctor. If you need a painkiller while you're taking lansoprazole it's fine to take paracetamol or co-codamol. u can take any painkillers with amoxicillin, just make sure u only mix ones that are compatible (ibuprofen and paracetamol are fine) if they are not enough try something like co codamol but dont take paracetamol at same time, tho u can take ibuprofen with it. If you're not sure or you have any questions about your blood test, ask your healthcare professional for advice.Never stop taking prescribed medicine unless you are told to do so by your healthcare team.Some medicines can affect the results of a blood test, but this does not necessarily mean that you need to stop taking your medicine.However, a doctor can take this into account when interpreting your test results, so you will not need to stop taking your medicine.If you're unsure, keep taking your medicine as prescribed and check with your doctor.You may also want to take your medicine with you to show the person doing your blood test.Herbal remedies, vitamins or supplements can also affect results, so tell your doctor if you take any of these.You should never stop taking prescribed medicine, unless you're told to do so by your doctor.Sometimes, you may need to stop taking a medicine before a blood test.If you're having a blood test to check whether your medicine is working, in most cases you should keep taking your medicine.For example, if you're taking medicine to lower your cholesterol level, you should keep taking it before your cholesterol blood test, as the result will show whether the medicine is working.