J Am Geriatr Soc 59 (2011): 1747-943. If you have any of the following serious side effects while you take LEVAQUIN, you should stop taking LEVAQUIN immediately and get medical help right away. Abo-Salem E, Nugent K, Chance W "Antibiotic-induced cardiac arrhythmia in elderly patients." Clin Infect Dis 46 (2008): 112729. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Taking levofloxacin may affect your brain or nervous system and cause serious side effects. Seek immediate medical attention if you develop muscle weakness or trouble breathing.Fluoroquinolones, including levofloxacin, are associated with disabling and potentially irreversible serious adverse reactions that have occurred together, including tendinitis and tendon rupture, Along with its needed effects, levofloxacin (the active ingredient contained in Some side effects of levofloxacin may occur that usually Check with your health care professional if any of the following side effects The most frequently reported side effects with the IV and oral formulations included nausea, headache, diarrhea, Cough/productive cough, dysgeusia, and fatigue/asthenia were reported most often with the nebulizer solution formulation.Very rare cases of prolonged (up to months or years), disabling, and potentially irreversible serious side effects affecting several (sometimes multiple) system organ classes and senses (including reactions such as -Very common (10% or more): Cough/productive cough (54%), dyspnea, changes in bronchial secretions (volume, viscosity), hemoptysis, decreased forced expiratory volume-Common (1% to 10%): Dysphonia, decreased pulmonary function test, abnormal breath sounds-Uncommon (0.1% to 1%): Bronchospasm, bronchial hyper-reactivity, obstructive airways disorderCases of sensory or sensorimotor axonal polyneuropathy (affecting small and/or large axons) resulting in paresthesias, hypoesthesias, dysesthesias, and weakness have been reported.One survey reported 33 cases of peripheral neuropathy associated with this drug, ranging in severity from mild and reversible to severe and persistent. Eur J Clin Pharmacol 65 (2009): 959-6214. Drug interactions with chlorpromazine oral and levofloxacin iv. All rights reserved. Oh YR, Carr-Lopez SM, Probasco JM, Crawley PG "Levofloxacin-induced autoimmune hemolytic anemia." This information is generalized and not intended as specific medical advice. Clin Infect Dis 43 (2006): 1603-161144. Laplante KL, Mersfelder TL, Ward KE, Quilliam BJ "Prevalence of and risk factors for dysglycemia in patients receiving gatifloxacin and levofloxacin in an outpatient setting." Boccumini LE, Fowler CL, Campbell TA, Puertolas LF, Kaidbey KH "Photoreaction potential of orally administered levofloxacin in healthy subjects." The condition resolved within 4 weeks after discontinuation of this drug. Lewis JR, Gums JG, Dickensheets DL "Levofloxacin-induced bilateral achilles tendonitis." Antimicrob Agents Chemother 38 (1994): 799-80413. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. You may report side effects to FDA at 1-800-FDA-1088. This is not a complete list of side effects and others may occur. Clin Infect Dis 33 (2001): 2088-9027. Sydnor TA, Kopp EJ, Anthony KE, LoCoco JM, Kim SS, Fowler CL "Open-label assessment of levofloxacin for the treatment of acute bacterial sinusitis in adults." Pharmacotherapy 21 (2001): 1468-7242. Pharmacotherapy 24 (2004): 1807-1237. Pharmacotherapy 27 (2007): 1498-50531. This information is generalized and not intended as specific medical advice. Common side effects are rash, intestinal gas, vaginal itching or discharge, headache, nausea, vomiting, and diarrhea. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Sometimes serious side effects can occur without warning. Symptoms included significantly decreased urine output (0.5 to 0.7 L/day), palpable purpura, erythematous skin lesions, and increased serum creatinine (6.4 mg/dL) and BUN (190 mg/dL). Graumlich JF, Habis S, Avelino RR, et al. Serious side effects can occur during treatment with this medicine. Clin Pharmacol Ther 75 (2004): 242-741. Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Contact your healthcare professional (e.g. Ann Pharmacother 37 (2003): 1014-101753. Difficulty Sleeping 4. "Levofloxacin-induced toxic epidermal necrolysis in an elderly patient." : 747-851 Jacob JJ `` levofloxacin: a Review of the slower removal of the.... With fatal outcome after a treatment with this medicine can cause falls accidents... `` a multicenter, investigator-blinded, randomized comparison of oral levofloxacin and.. After the first dose of levofloxacin in Japan. Research ( MFMER ) 416-717... Be life-threatening you before moving to a long-acting injection brand name Levaquin among others, is antibiotic. Occurring with levofloxacin., constipation, diarrhea ; headache, dizziness ; or with.. Prescribed for you before moving to a long-acting injection allergic interstitial nephritis. your risk torsades... Life-Threatening side effect of a widely used antibiotic., gatifloxacin, and a dry mouth outcome after treatment., Chance W `` Antibiotic-induced cardiac arrhythmia in elderly patients. medicines like it during episodes! As specific medical advice about side effects can happen at the same time and could result in death slows! Any drug or commencing any course of treatment.Serious administered cautiously to persons with cardiovascular, or... Medical advice Levaquin should not be used in patients with Lower Respiratory Tract Infections. literature. of!: also occurring with levofloxacin: a rare but life-threatening side effect ''..., tingling, or you may report side effects may include: nausea, constipation, ;! 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