How is Clotrimazole Lozenge Supplied. …effective as clotrimazole troches used five times daily . There are no data from adequate and well-controlled trials to establish the safety and efficacy of this product for prophylactic use in patients immunocompromised by etiologies other than those listed in the previous sentence. Clotrimazole troches should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.Safety and effectiveness of clotrimazole in children below the age of 3 years have not been established; therefore, its use in such patients is not recommended.The safety and efficacy of the prophylactic use of clotrimazole troches in children have not been established.Clinical studies of clotrimazole did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. No teratogenic effects have been demonstrated in animal studies at doses up to 200 times the human dose; however, doses of 100 times the adult human dose were embryotoxic in rats and mice. Copy the URL below and paste it into your RSS Reader application. ]The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Find patient medical information for Clotrimazole Topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Do not chew, crush, or swallow clotrimazole lozenges. Periodic assessment of hepatic function is advisable particularly in patients with pre-existing hepatic impairment.Since patients must be instructed to allow each troche to dissolve slowly in the mouth in order to achieve maximum effect of the medication, they must be of such an age and physical and/or mental condition to comprehend such instructions.An 18 month dosing study with clotrimazole in rats has not revealed any carcinogenic effect.Clotrimazole given orally to mice from nine weeks before mating through weaning at a dose 120 times the human dose was associated with impairment of mating, decreased number of viable young, and decreased survival to weaning. NDC 0054-4146-23: Bottle of 140 Troches. No effects were observed at 60 times the human dose. Along with its needed effects, clotrimazole (the active ingredient contained in Clotrimazole … [See USP Controlled Room Temperature.] Use clotrimazole exactly as directed. Clotrimazole Troche (clotrimazole lozenge), 10 mg. 0054-4146-22: Bottles of 70. Side effects requiring immediate medical attention. Clotrimazole lozenges are used to treat yeast infections of the mouth in adults and children 3 years of age and older. (See Clotrimazole is contraindicated in patients who are hypersensitive to any of its components.Clotrimazole is not indicated for the treatment of systemic mycoses including systemic candidiasis.Abnormal liver function tests have been reported in patients treated with clotrimazole troches; elevated SGOT levels were reported in about 15% of patients in the clinical trials. The recommended dose is one troche five times a day for fourteen consecutive days. -Prophylaxis to reduce the incidence of or… Some of the dosage forms listed on this page may not apply to the brand name Clotrimazole Troche.. For the Consumer. Each Clotrimazole Troche (lozenge) USP contains 10 mg clotrimazole USP [1-(o-chloro-α,α-diphenylbenzyl) imidazole], a synthetic antifungal agent, for topical use in the mouth.The troche dosage form is a large, slowly dissolving tablet (lozenge) containing 10 mg of clotrimazole USP dispersed in croscarmellose sodium, dextrates, magnesium stearate, microcrystalline cellulose and povidone.Clotrimazole is a broad-spectrum antifungal agent that inhibits the growth of pathogenic yeasts by altering the permeability of cell membranes.