We will see how this medicine works for me overtimeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.We comply with the HONcode standard for trustworthy health information - If you have normal symptoms and feel a cold sore coming on, you can begin using most OTC treatments with immediate effect.Side effects that occur due to the use of topical cold sore treatments are rare. Here, you’ll find some of the best products on the market for soothing and healing cold sores. This systematic review of the clinical studies evaluating the three topical treatments, acyclovir, penciclovir, and docosanol, also supports the notion that their efficacy compared to placebo is marginal at best (shortening the duration of pain by <24 hours), although the three topical antiherpetic drugs have no serious adverse reactions and are safe to use. Talk to your doctor.I used to get cold sores four or five times a year, sometimes more often (especially when I was dealing with the stress of college). Acyclovir (Zovirax), valacyclovir (Valtrex), famciclovir (Famvir), penciclovir (Denavir), and docosanol (Abreva) are the drugs of choice for HSV infections. Other shingles symptoms include headache, fever, nausea, and body aches. Data sources include IBM Watson Micromedex (updated 2 Sep 2020), Cerner Multum™ (updated 1 Sep 2020), Wolters Kluwer™ … If the pain doesn’t start to subside, even with OTC medication, consult with your doctor for further treatment. Money Back? 0. Prescribed for Herpes Simplex,... In a few days, that blister will burst. This does not necessarily mean no interactions exist. Valacyclovir thus is active against the same viruses as acyclovir, but valacyclovir has a longer duration of action than acyclovir and can be taken fewer times each day. Here are a few more options for you to check out.Last update on 2020-09-12 / Affiliate links / Images from Amazon Product Advertising APIQuantum Health Lip Clear Invisible Cold Sore Bandage Review Abreva rated 4.5/10 vs Acyclovir rated 8.3/10 in overall patient satisfaction. Thanks to the Internet, you can find different providers, compare prices and choose the best conditions. Regularly using OTC medication can also help to prevent the virus from flaring up. If you want real results during a herpes outbreak, you need an oral medication. Certain...Medical marijuana (medical cannabis) is a medicine that is plant based. FDA Approved? This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Abreva is used to treat cold sores/fever blisters on the face or lips. No known drug interactions. Read Review It didn't seem to do anything; the cold sores kept coming. Typically, it takes anywhere from 2-4 days for the blister to become significantly less noticeable. Available for Android and iOS devices.View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.So unfortunately I have had cold sore outbreaks for years. Abreva may also be used for purposes not listed in this medication guide. Compare different prices to make the best decision. It’s easy to apply and makes life more tolerable.You can expect the use of OTC treatments to achieve the following:Reducing the time it takes for a cold sore is what most people want. Reviews Visit the MedicineNet does not provide medical advice, diagnosis or treatment. While it may not help to speed up healing, it can get rid of the pain that makes the blister so bad in the first place.If you don’t regularly experience flare-ups, the single-use design is good value.