If signs or symptoms of congestive heart failure occur or worsen during administration of itraconazole, reassess the benefit and risk of continuing treatment.Drug Interactions:Coadministration of certain drugs that are metabolized by human CYP3A4 enzymes are contraindicated with itraconazole because plasma concentrations of such drugs are increased, which may also increase or prolong both the pharmacologic effects and/or adverse reactions to these drugs.Coadministration with colchicine, fesoterodine, and solifenacin is contraindicated in subjects with varying degrees of renal or hepatic impairment, and coadministration with eliglustat is contraindicated in subjects that are poor or intermediate metabolizers of CYP2D6 and in subjects taking strong or moderate CYP2D6 inhibitors.Increased plasma concentrations of some of these drugs can lead to QT prolongation and/or ventricular tachyarrhythmias, including occurrences of torsades de pointes, a potentially fatal arrhythmia.Congestive Heart Failure, Cardiac Effects and Drug Interactions: If signs or symptoms of congestive heart failure occur during administration of itraconazole oral solution, continued itraconazole use should be reassessed. All rights reserved. Drugs 52 (1996): 2533. Janssen Pharmaceutica, Titusville, NJ. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Cleveland KO, Campbell JW "Hallucinations associated with itraconazole therapy." And the reason why many individuals who take these drugs suffer side effects is that the role of DHT in the body is more than to simply cause hair loss. Concomitant administration can cause the plasma levels of the concomitant drug to increase. Both are proven to work. Dutasteride, which comes in dutasteride capsules, has been known to help treat hair loss effectively in men and eat also offers a host of other health benefits. They concluded that dutasteride is more effective at treating hair loss and shows similar rates of adverse reactions, especially in sexual dysfunction. Dutasteride vs Finasteride. J Am Acad Dermatol 23 (1990): 593-6015. Dutasteride Side Effects. In a current hair loss study for Avodart/Dutasteride, results have been released to the American Academy of Dermatology and the results are very promising. Clin Pharmacokinet 40 (2001): 441-7215. However, dutasteride may cause allergic reactions, and increases the risk of high-grade prostate cancer. They have been submitted to the FDA. One of the co-authors of the study was a Dr. Sergio Vañó-Galván from Spain. Finasteride is the older of the two drugs and is the only one approved by the FDA for the treatment of hair loss in men. Dutasteride has been known to reduce sexual potency amongst its users. Some of the dosage forms listed on this page may not apply to the brand name Sporanox.. In addition, coadministration with colchicine, fesoterodine, and solifenacin is contraindicated in subjects with varying degrees of renal or hepatic impairment, and coadministration with eliglustat is contraindicated in subjects that are poor or intermediate metabolizers of CYP2D6 and in subjects taking strong or moderate CYP2D6 inhibitors. The more common side effects that can occur with dutasteride include: GlaxoSmithKline, Research Triangle Park, NC. "Product Information. Gelfand MS, Cleveland KO "Acute congestive heart failure and death secondary to itraconazole therapy." Cerner Multum, Inc. "UK Summary of Product Characteristics." Both are proven to work. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Other side effects not listed may also occur in some patients.