LeRoy EC, Medsger TA. The following list of medications are in some way related to, or used in the treatment of this condition. By contrast, no vigilance impairment was found during sertraline treatment. Search for other works by this author on: Davis MDP, O'Fallon WM, Rogers RS III, Rooke TW. As some patients with Raynaud's phenomenon experienced marked clinical improvement in their symptoms when given SSRIs [Jaffe IA. I was treated for depression 5 years ago with Lovan (fluoxetine) 20 mgs, it helped my depression and made a big improvement to my Raynauds as well . Erythromelalgia is a rare painful disorder of the extremities characterized by redness, a burning sensation and an increase in skin temperature exacerbated by exposure to heat [SSRIs inhibit the reuptake of serotonin with a decreased storage of 5‐hydroxytryptamine in platelets leading to symptomatic platelet dysfunction. How do you food prep without ... This might have been partly due to the lower doses used (40 mg daily), as doses of 60 mg have been described in treating refractory Raynaud's phenomenon.The relatively small number of patients evaluated in this pilot study means that subgroup analysis must be interpreted cautiously. Jaffe IA. Previous studies have suggested that escitalopram is superior to citalopram in efficacy. The handbook papers are continuously published ONLINE FIRST in the SPRINGER Reference system: http://link.springer.com/book/10.1007/978 Participants of a group therapy program aiming to improve coping with professional stress will be invited to participate in this study. About Raynaud's Syndrome: Raynaud's Syndrome is a condition in which cold temperatures or strong emotions cause blood vessel spasms that block blood flow to the fingers, toes, ears, and nose. To compare fluoxetine, a selective serotonin reuptake inhibitor, with nifedipine as treatment for primary or secondary Raynaud's phenomenon. What is Raynauds phenomenon? Patients with severe symptoms or intolerance to available therapies have prompted exploration of alternative therapies, including endothelin antagonists, phosphodiesterase-5 inhibitors, antioxidants, newer vasodilators, statins, and botulinum toxin. Like most drugs, SSRIs have not been widely tested in clinical trials Subchronic treatment with the selective serotonergic reuptake inhibitors (SSRIs) fluoxetine, venlafaxine and paroxetine, but not sertraline, were previously shown to specifically impair vigilance performance. Occupational silica exposure in an Australian systemic sclerosis cohort Some of the variability in the response to treatment may also have been due to genetic differences in metabolic or signalling pathways related to serotonin, and this possibility may be addressed in future studies. Patients were randomized to receive either fluoxetine 20 mg daily or nifedipine LA 40 mg daily for 6 weeks, after which assessments were repeated. I have a personal question. However this treatment is not always accepted or contraindicated for a variety of reasons. To compare fluoxetine, a selective serotonin reuptake inhibitor, with nifedipine as treatment for primary or secondary Raynaud's phenomenon. Is it normal with Raynaud's for the fingers to go numb just getting something from the fridge or washing some fruit? von Willebrand factor, thrombomodulin, thromboxane, beta‐thromboglobulin and markers of fibrinolysis in primary Raynaud's phenomenon and systemic sclerosis. Treatment of Raynaud's phenomenon with ketanserin, a selective antagonist of the serotonin2 (5HT2) receptor. After a 2‐week washout period, patients crossed over to receive 6 weeks of treatment with the other drug. Method: Erythromelalgia: response to serotonin reuptake inhibitors. Search for other works by this author on: Mean (+Reduction in frequency of attacks of Raynaud's phenomenon after treatment. These newer therapies provide the focus for this review.Raynaud, digital ulcers and calcinosis are frequent manifestations of patients with systemic sclerosis. Thank you for submitting a comment on this article. However, here is the quoted information.I went back online and tried again and was successful in copying it this time!I take Prozac and it did help my Raynaud's. Search for other works by this author on: Search for other works by this author on: Mean (+More objective evidence of the severity of Raynaud's phenomenon and the response to treatment was obtained from thermographic assessment of the patients at the start of the trial and after each treatment arm. major depression in which escitalopram was compared with active controls (citalopram, fluoxetine, paroxetine, sertraline and venlafaxine XR [extended release]) were pooled. Fluoxetine selectively inhibits presynaptic serotonin reuptake with minimal or no effect in the reuptake of norepinephrine or dopamine. 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