Select one or more newsletters to continue. Glipizide belongs to the class of drugs known as sulfonylureas. Most non cardio selective beta-blockers increase the incidence and severity of hypoglycaemia.The use of angiotensin-converting enzyme inhibitors may lead to an increased hypoglycaemic effect in diabetic patients treated with sulfonylureas.The use of cimetidine may be associated with a reduction in post prandial blood glucose in patients treated with glipizide.The hypoglycaemic action of sulfonylureas, in general may also be potentiated by monoamine oxidase inhibitors, quinolones and drugs that are highly protein bound, such as sulfonamides, chloramphenicol, probenecid, coumarins and fibrates.When such drugs are administered to (or withdrawn from) a patient receiving glipizide, the patient should be observed closely for hypoglycaemia (or loss of control).The following products could lead to hyperglycaemia:Diabetogenic effect of danazol. Important Information It is used all the time for the treatment of non-insulin dependent diabetes. 5 mg; 10 mg; Tablet, extended-release. Mild hypoglycaemic symptoms without loss of consciousness or neurologic findings should be treated actively with oral glucose and adjustments in drug dosage and/or meal patterns. Patients treated with miconazole (see section 4.5).Since glipizide belongs to the class of sulfonylurea agents, caution should be used in patients with G6PD-deficiency. GLUCOTROL (glipizide) is an oral blood-glucose-lowering drug of the sulfonylurea class. They have a similar chemical structure and are often used to … Your doctor may occasionally change your dose. Pharmacotherapeutic group: Drugs used in diabetes, blood glucose lowering drugs excl. Properly discard this product when it is expired or no longer needed. Consult your Are you planning to see a doctor about switching your medication?Are you planning to see a doctor about switching your medication?Selected from data included with permission and copyrighted by First Databank, Inc. insulins, sulfonylureas, ATC code: A10BB07Glipizide is an oral blood-glucose-lowering drug of the sulfonylurea class. 1 High Alert glipiZIDE (glip-i-zide) Glucotrol,GlucotrolXL ... convert gradually by receiving glipizide and a 25–30% reduction in insulin dose Use Older adults may be more sensitive to the side effects of this drug, especially If someone has overdosed and has serious symptoms such as passing out or Keep all regular medical and laboratory appointments. This phenomenon is known as secondary failure, to distinguish it from primary failure in which the drug is ineffective in an individual patient when first given. If it cannot be avoided, warn the patient and step up self monitoring of blood glucose and urine. You may report side effects to FDA at 1-800-FDA-1088.Sometimes it is not safe to use certain medications at the same time. November 25, 2016 by DiabetesBro. Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. 2 years when stored in Polypropylene containers with polyethylene caps (Securitainers)Store below 25°C and keep in the original package in order to protect from light.Glipizide 5 mg Tablets are available either in cartoned blister packs, high density polyethylene containers or in polypropylene containers with polyethylene caps.Either 10 or 14 tablets are packed in PVC/PVDC/Aluminium foil blister strips. The primary mode of action of glipizide is the stimulation of insulin secretion from the beta-cells of pancreatic islet tissue. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. CAPITALS indicate life-threatening, underlines indicate most frequent. The metabolic and excretory patterns are similar with the two routes of administration, indicating that first-pass metabolism is not significant. Glipizide is available under the following different brand names: Glucotrol, Glucotrol XL, and Minodiab. This site uses cookies. All sulfonylurea agents are capable of producing severe hypoglycaemia. They should also be informed about the importance of adherence to dietary instructions, of a regular exercise program, and of regular testing of urine and/or blood glucose.The risks of hypoglycaemia, its symptoms and treatment, and conditions that predispose to its development should be explained to patients and responsible family members.