Atezolizumab plus bevacizumab versus sunitinib in patients with previously untreated metastatic renal cell carcinoma (IMmotion151): a multicentre, open-label, phase 3, randomised controlled trialGlobal Burden of Disease Causes of Death CollaboratorsRoyal Australian and New Zealand College of Obstetricians and GynaecologistsRoyal Australian and New Zealand College of Obstetricians and GynaecologistsBaseline characteristics (intention-to-treat population)Outcomes at 6 weeks post-delivery based on data from telephone follow-up and hospital records (intention-to-treat population)Risk in amoxicillin and clavulanic acid group/risk in placebo group.Risk in amoxicillin and clavulanic acid group/risk in placebo group.Secondary outcomes at 6 weeks post-delivery based on data from questionnaire (intention-to-treat population)Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Denominator is all women who have attempted intercourse since giving birth (n=544 amoxicillin and clavulanic acid group, n=514 control group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Difference in medians for hospital bed stay to discharge.Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Risk ratio (risk in amoxicillin and clavulanic acid group/risk in placebo group).Denominator is all women who have attempted intercourse since giving birth (n=544 amoxicillin and clavulanic acid group, n=514 control group).Difference in medians for hospital bed stay to discharge.Royal Australian and New Zealand College of Obstetricians and GynaecologistsRoyal Australian and New Zealand College of Obstetricians and GynaecologistsRoyal Australian and New Zealand College of Obstetricians and Gynaecologists
However, the results are likely to be comparable if antibiotics with a similar spectrum of activity are used and would therefore be generalisable to women who are allergic to penicillin. Dr Sillender is part of the Glengarry Private Hospital Know My Midwife program.Gynaecology, Obstetrics, Obstetrics and GynaecologyDr Vashevnik prioritises the wishes of the mother first and provides choice and control over their birthing experience. Author information: (1)Department of Obstetrics and Gynaecology, Ramsay Health Care, Joondalup Health Campus, Joondalup, Western Australia, Australia. Castor oil packs may improve some symptoms of constipation, according to a 2011 study from Complementary Therapies in Clinical Practice. EQ-5D-5L=five-level EuroQol-5D questionnaire.Side-effects of the trial intervention were reported by three women. The trial protocol, statistical analysis plan, and other study documents are also available on request through this route. CP, VC, LL, and EJ developed the analysis plan. Our post-hoc subgroup analysis (WHO guidelines for the prevention of maternal infection,Trends in operative vaginal delivery, 2005–2013: a population-based study.Global perspectives on operative vaginal deliveries.In this trial, we defined suspected or confirmed maternal infection using a composite outcome, including a new prescription of antibiotics for confirmed or suspected infection, which can be interpreted as equating to a clinical diagnosis of infection. Am J Emerg Med. This trial was done in a high-income setting, but given the pragmatic nature of the trial and the simple intervention, the findings are likely to be generalisable to low-income and middle-income settings in which intravenous antibiotics are available. Epistaxis is a common presentation to the emergency department (ED) 1 that can be challenging and time consuming. The primary outcome measure is the PTSD Checklist … All authors formed the fast-track writing group and edited and approved the final version of the Article. All other authors have no competing interests to declare. The need for a broadly applicable, effective strategy for primary prevention is paramount. This clinical diagnosis of infection drove the overall outcome and resulted in a substantially higher than anticipated percentage of events albeit with an effect size in keeping with our previous assumption, reflecting the high rate of perineal wound infection, which was not measured in the previous trial, and on which we based our anticipated event number. Until these analyses are completed, there is no indication for administration of more than a single dose of prophylactic antibiotic, or for predelivery administration.