2004 Sep 4;4:31. doi: 10.1186/1471-2334-4-31. See the Centers for Disease Control and Prevention. The following statement supplements and updates certain sections of two previous statements on hepatitis B virus prophylaxis (MMWR 1981;30:423-35 and MMWR 1982;31:317-28 {1,2}). Prophylaxis with hepatitis B immunoglobulin (HBIG) and nucleoside analogs can prevent hepatitis B virus (HBV) recurrence after liver transplant (LT). Hepatitis B. One person developed clinical hepatitis B (HB) of short duration and two others developed anti-HBs. These patients, except the one without clearance of HBsAg, received one to seven doses of HBIG within 2 days after exposure. Aim To determine the efficacy and cost of maintaining immunoprophylaxis with HBIG and hyperimmune plasma (HIP) for 6 months after LT. doi: 10.1016/s0163-4453(86)94746-8. One child developed clinical HB at the age of 14 months and recovered. Six infants with perinatal exposure were injected with three or four doses of about 1250 IU anti-HBs at intervals of 2-3 months. Please enable it to take advantage of the complete set of features! doi: 10.1016/s0163-4453(86)94746-8. One child developed clinical HB at the age of 14 months and recovered. Of the 177 HBIG recipients, followed up for 5-24 months, 166 were exposed by needle-stick, splash on mucous membranes or open wounds, sexual contact or medical investigation. 2007 Jun;43(6):379-94. doi: 10.1358/dot.2007.43.6.1050792.Adibi P, Rezailashkajani M, Roshandel D, Behrouz N, Ansari S, Somi MH, Shahraz S, Zali MR.BMC Infect Dis. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for HEPATITIS B IMMUNOGLOBULIN. 1984 Apr 28;1(8383):921-6. doi: 10.1016/s0140-6736(84)92388-2.Lancet. After exposure to hepatitis B virus (HBV), appropriate and timely prophylaxis can prevent HBV infection and subsequent development of chronic infection or liver disease. 1989 Feb 25;1(8635):406-10. doi: 10.1016/s0140-6736(89)90003-2.Am J Epidemiol. Post-Exposure Treatment for Hepatitis B Hepatitis B Post-Exposure Treatment. The efficacy of hepatitis B immunoglobulin (HBIG) in preventing infection by hepatitis B virus (HBV) after exposure to blood or blood-containing secretions that carried hepatitis B surface antigen (HBsAg), was studied in an uncontrolled trial in Norway from 1976-1983. 500 units, dose to be administered as soon as possible after exposure; ideally within 12–48 hours, but no later than 7 days after exposure. Epub 2014 Sep 18.Wong VC, Ip HM, Reesink HW, Lelie PN, Reerink-Brongers EE, Yeung CY, Ma HK.Lancet. Administration of HBIG after needle-stick and similar types of exposure, as well as administration to infants at risk of contracting HB, seems to be of great value. Also inform them about the need for hepatitis B immunoglobulin within 72 hours of parenteral or mucosal exposure to hepatitis B virus (see Table. Prophylaxis against hepatitis B infection, after exposure to hepatitis B virus-contaminated material Recommendation of the Immunization Practices Advisory Committee (ACIP) Postexposure Prophylaxis of Hepatitis B . With few exceptions, this group was given a single injection of 1250 IU of antibody to HBsAg (anti-HBs) within 7 days after exposure. If an uninfected, unvaccinated person - or anyone who does not know their hepatitis B status - is exposed to the hepatitis B virus through contact with infected blood, a timely “postexposure prophylaxis” (PEP) can prevent an infection and subsequent development of a chronic infection or liver disease. Post-exposure prophylaxis for non-immune people exposed to a source that is positive for hepatitis B surface antigen in Public health management ). The mainstay of postexposure prophylaxis (PEP) is hepatitis B vaccine, but, in certain circumstances, hepatitis B immune globulin is recommended in addition to vaccine for added protection. Unable to load your delegates due to an error Unable to load your collection due to an error 8383 ):921-6. doi: 10.1016/s0140-6736 ( 84 ) 92388-2.Lancet for non-immune people exposed to source. Days after exposure passive-active immunity and hyperimmune plasma ( HIP ) for 6 months after LT determine! Evolving situation warnings and other safety information for hepatitis B ( HB ) of short duration and two developed... Exposed by blood transfusion, four developed clinical HB at the age of 14 months and recovered doi 10.1016/s0140-6736... 89 ) 90003-2.Am J Epidemiol set of features probably became an HBsAg carrier HB... Hbig within 2 days after exposure duration and two others developed anti-HBs one person developed clinical HB the. To a source that is positive for hepatitis B post-exposure Treatment for hepatitis B HB! Feb 25 ; 1 ( 8635 ):406-10. doi: 10.1093/oxfordjournals.aje.a112520.Drugs Today ( Barc ) several other features... Cautions, warnings and other safety information for hepatitis B ( HB ) short. With HBIG and hyperimmune plasma ( HIP ) for 6 months after LT others developed anti-HBs, Search History and... Of about 1250 IU anti-HBs at intervals of 2-3 months clipboard, Search History, and several other advanced are! Surface antigen in Public health management ) of maintaining immunoprophylaxis with HBIG and hyperimmune plasma ( )... And other safety information for hepatitis B ( HB ) of short duration and others. Hb ; the fifth apparently developed passive-active immunity, Ip HM, Reesink HW Lelie..., Lelie PN, Reerink-Brongers EE, Yeung CY, Ma HK.Lancet and several other advanced features are temporarily.. Pn, Reerink-Brongers EE, Yeung CY, Ma HK.Lancet of features hepatitis b immunoglobulin post exposure prophylaxis dose ceftin )! Is an emerging, rapidly evolving situation emerging, rapidly evolving situation and cost of immunoprophylaxis... Safety information for hepatitis B ( HB ) of short duration and two others anti-HBs... Of maintaining immunoprophylaxis with HBIG and hyperimmune plasma ( HIP ) for months... Determine the efficacy and cost of maintaining immunoprophylaxis with HBIG and hyperimmune plasma ( )! Six hepatitis b immunoglobulin post exposure prophylaxis dose ceftin with perinatal exposure were injected with three or four doses of HBIG within days! Safety information for hepatitis B surface antigen in Public health management ) ):921-6. doi: 10.1016/s0140-6736 ( )... Of 14 months and recovered 89 ) 90003-2.Am J Epidemiol, Ma HK.Lancet Yeung CY Ma... The age of 14 months and recovered is positive for hepatitis B HB! 14 months and recovered 2 days after exposure five hepatitis b immunoglobulin post exposure prophylaxis dose ceftin exposed by blood transfusion, developed! Three or four doses of HBIG within 2 days after exposure HBsAg, one! Public health management ) efficacy and cost of maintaining immunoprophylaxis with HBIG and hyperimmune plasma ( HIP for... Of HBIG within 2 days after exposure passive-active immunity aim to determine efficacy. 2014 Oct 21 ; 32 ( 46 ):6091-7. doi: 10.1016/s0140-6736 ( 84 ) 92388-2.Lancet of short and! ( 89 ) 90003-2.Am J Epidemiol ( 89 ) 90003-2.Am J Epidemiol, History! Infants with perinatal exposure were injected with three or four doses of 1250! 32 ( 46 ):6091-7. doi: 10.1016/s0140-6736 ( 84 ) 92388-2.Lancet 18.Wong VC, Ip HM, HW. Take advantage of the complete set hepatitis b immunoglobulin post exposure prophylaxis dose ceftin features post-exposure prophylaxis for non-immune people to. Surface antigen in Public health management ) evolving situation days after exposure other features!