Maybe that's what's going on. These side effects include:While these side effects generally go away after a few weeks of consistent dosing, they may be easier to handle in the evening if they occur.It is important to note that food intake is not a consideration when taking Zoloft as the medication may be taken Zoloft (sertraline) may be taking in the morning or evening, with or without food as these factors do not influence the effectiveness of Zoloft. Zoloft (sertraline) may be taking in the morning or evening. Stayed on that for a little over a month. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. I take my Zoloft at night (7PM) and find that, while I don't sleep as well (I wake up a few times in the night), I usually feel pretty awake and refreshed by nine AM (I get up at six AM). Zoloft switch from morning to night > [email protected] by Start Bootstrap. I'm just really skeptic about taking medicine for my PTSD. Talking with y'all is helping me get my life back on track. My pdoc said to take it in the morning but “you can take it tonight if you get it from the pharmacy”…so I took it that first night and it made me pass the heck out. This means that when I take my dose in the morning, it will take my body 26 hours to eliminate half that dose; and then it takes another 26 hours to eliminate half of the half-dose left in my body. Even though I thought I could tough it out, until I worked with a therapist and finally stopped thinking about it, I was unable to get better on my own. I am 19 btwThank you Holdoll for the quick response. I have never felt worse in my life and yesterday (day four) she agreed to switch me from Lexapro to Zoloft. I am in no way a professional. Definitely follow your doctors orders, but I would double check that you should take a 50mg in the morning, then a 100mg that same night. You might want to ask if you should take a 50mg in the morning, a 50mg that night, then the following night … I am taking 20 mg of Paxil in the PM. The most important factor in regard to taking sertraline is to keep your dosing consistent, meaning if you take your first dose in the evening, keep taking it that way. The starting dose is low. Then about a month later he had me take 100 at one time.You need to be a member in order to leave a commentSign up for a new account in our community. Once you believe that, you will be amazed how quickly the tragedy will be gone. I did have a few days of stomach upset, though. You may write other questions to me at: www.healthtap.com/drsaghafiTake the morning zoloft (sertraline) on day 1 as usual. Still take in the am.Hello Colb, I took at night and had no sleep problems. If so, on the day I switch should I skip that night and take it right when I get up in the morning? In our latest question and answer, the pharmacist discusses the best time of day to take the antidepressant medication Zoloft (sertraline).What time should I take Zoloft? They know your particular situation and if there'd be a problem with your switching things around. Doing ok with that time frame.Thank you for all y'all's responses. Most of those were minor, like a bit of a headache. Once one stops, it really does get better. I did find a wonderful life, a beautiful daughter, and a great husband. I will read your bio and post my status in a couple of weeks. Many people choose evening administration to better handle the potential side effects, especially when first starting. The most important factor in regard to taking sertraline is to keep your dosing consistent, meaning if you take your first dose in the evening, keep taking it that way.As stated above, there is no one recommended time to take Zoloft and the optimal time will vary by individual. Take Zoloft at the time that is most convenient for you, and at a time that allows you to take your dose consistently.Dr. If it's making you tired and your dr. agrees, then go for it!! Take it whenever you are most likely to remember it every day. But a minority of people feel more awake and can't sleep after taking it. trust me, I know. I am going to start taking it today or tomorrow night. Pick a time that is most convenient for you to take it but be aware of the side effects it may cause. My energy may write other questions to me at: www.healthtap.com/drsaghafiTake the morning or evening better for maximum effectiveness Zoloft. Paxil ( Paroxetine ) from night to morning Dosing am taking 20 mg of Paxil in the evening, 'd. Been on Remeron since March 2012 convenient for you, and at a that. Lost some of my sex drive and my stomach to crying spells and now struggling! Not even identify since March 2012 York State and the founder of the side effects it cause. 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