Tell your doctor if you are pregnant.You should not breast-feed while using hydrocortisone.Hydrocortisone is injected into a muscle, or given as an infusion into a vein. Long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased Do not receive a "live" vaccine while using hydrocortisone. Also, any infection you get may be harder to treat. Multiple Studies Confirm Steroids Can Fight Severe COVID-19 This dose may be repeated at intervals of 2, 4 or 6 hours as indicated by the patient's response and clinical condition.In general high-dose corticosteroid therapy should be continued only until the patient's condition has stabilised - usually not beyond 48 to 72 hours. Adverse effects on fertility in rats with corticosterone were observed in males only and were reversible. How dose reduction should be carried out depends largely on whether the disease is likely to relapse as the dose of systemic corticosteroids is reduced. Steroids may reduce the effects of anticholinesterases in myasthenia gravis. The vaccine may not work as well and may not fully protect you from disease. 0000049225 00000 n Thrombosis including venous thromboembolism has been reported to occur with corticosteroids. Tell your doctor if your child is not growing at a normal rate while using hydrocortisone.This is not a complete list of side effects and others may occur. Convulsions have been reported with concurrent use of corticosteroids and ciclosporin. 0000023830 00000 n As a result corticosteroids should be used with caution in patients who have or may be predisposed to thromboembolic disorders.Particular care is required when considering the use of systemic corticosteroids in patients with the following conditions and frequent patient monitoring is necessary.1. This means that sodium content has to be taken into consideration by patients on a controlled sodium diet for dose above 370 mg of hydrocortisone. Hypoadrenalism may, in theory, occur in the neonate following prenatal exposure to corticosteroids but usually resolves spontaneously following birth and is rarely clinically important. 0000017955 00000 n Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (Avoid being near people who are sick or have infections. As with all drugs, corticosteroids should only be prescribed when the benefits to the mother and child outweigh the risks. In patients who have received more than physiological doses of systemic corticosteroids (approximately 30 mg hydrocortisone) for greater than 3 weeks, withdrawal should not be abrupt. 0000041374 00000 n Gastro-intestinal diseases. Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Along with its needed effects, a medicine may cause some unwanted effects. 0000003907 00000 n However, using this medicine during pregnancy may cause a hormone deficiency in the newborn. For instructions on administration, see section 4.2.For IV infusion, the following solutions can be used: dextrose 5% in water, isotonic saline solution or 5% dextrose in isotonic saline solution if patient is not on sodium restriction.Any unused medicinal product or waste material should be disposed of in accordance with local requirements.To bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER).