In this case, it’s important to take only the prescribed dose, and these combo drugs should only be taken for the shortest possible periods to avoid damage to the kidneys.To sum up, is codeine bad for you? The liver is a powerhouse organ, performing a variety of tasks that are essential to maintaining good health. In some cases, the risks of medicines become greater the longer you use them.So what about codeine? Taking baclofen with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. These side effects dissipate over time and aren’t considered severe in most cases.Other serious side effects possible with codeine include adrenal problems, low blood pressure, and overdose. Baclofen is a muscle relaxant and antispastic used for treating spasm of skeletal muscles, muscle clonus, rigidity, and pain caused by multiple sclerosis.Baclofen is also injected into the spinal cord to treat severe spasticity, spinal cord injuries, and other spinal cord diseases. Again, not on its own, but it is if it’s used excessively in a combination medicine that includes something like ibuprofen, which is an NSAID.Seeking addiction treatment can feel overwhelming. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.. Other drugs may affect baclofen, including prescription and over-the-counter medicines, vitamins, and herbal products. It’s considered fairly safe, at recommended doses, but if you take acetaminophen in excess, it can cause serious health problems. No, not on its own, but acetaminophen is, so be aware of this with combination medications.Certain medications can change kidney function and can be toxic to the kidneys and ultimately lead to renal failure in serious cases. Not if it’s taken as prescribed, for a short period of time to treat pain. An overdose of codeine or any other opioid occurs when someone takes such a large dose that it slows their respiration to a dangerous level, or breathing stops altogether. We publish material that is researched, cited, edited and reviewed by licensed medical professionals. Is codeine bad for your liver? Avonex 2001-2004. Codeine on its own isn’t bad for your liver, but when it’s used in combination with other medications, it can be. More specifically, is codeine bad for your liver and kidneys?Below is an overview of what codeine is and how it works as well as answers to the questions.Codeine is a controlled substance, which means it isn’t available over-the-counter, and it has the potential for addiction. I've been taking it for years. These include ibuprofen, and these drugs are available over the counter, much like acetaminophen.They can also be included in combination drugs that include codeine. This is how codeine can help with pain. Copaxone 2006-2009. The main risk of selegiline is heart disease for patients with a history of heart attacks or those who use other medicines that affect the heart. Most people feel it as a dull, throbbing sensation in the upper right abdomen. Was talking with some people yesterday at an MS support groups. Not on its own, but it can be when it’s included in prescription medicines with substances like acetaminophen. Usual Adult Dose for Spasticity. One example of this is with NSAIDs or nonsteroidal anti-inflammatory drugs. See below: Baclofen use is not bad on your kidneys, however if you have bad kidneys, then the dose should be decreased or it should be avoided depending on sever ... Read More 0 It should not be used in place of the advice of your physician or other qualified healthcare provider. Codeine is not necessarily bad for you if you take it exactly as prescribed and for a short period of time. This is why it’s so important for people taking codeine-acetaminophen combination drugs to follow dosing instructions. The liver processes acetaminophen, and if you take too much, it can cause liver toxicity.Acetaminophen in large amounts has been linked to acute liver failure and death. mark s. Abusing codeine can also cause cardiac issues or sudden death.People who abuse codeine may experience a euphoric high, but also changes in consciousness and motor function and all of the risks of codeine are heightened not only with high doses, but if the drug is combined with other substances that slow the central nervous system.Long-term effects of codeine can include sleep disturbances, pain when not using codeine, and seizures.This is a bit of a complex question.