These drugs are often used to treat similar conditions.Ezetimibe blocks the amount of cholesterol that’s absorbed from your intestines. Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Ezetrol tablets contain the active ingredient ezetimibe, which is a medicine used to lower high cholesterol levels - get trusted advice on its use, warnings and side effects Quantity of side effects 60%. This can be harmful or prevent the drug from working well.To help avoid interactions, your doctor should manage all of your medications carefully. Ezetimibe tablets are for patients who cannot control their cholesterol levels by diet and exercise alone. Talk to your doctor about other drug options that may work for you.© 2005-2020 Healthline Media a Red Ventures Company. The independent effect of raising HDL-C or lowering TG on the risk of coronary and cardiovascular morbidity and mortality has not been determined.Ezetimibe reduces total-C, LDL-C, Apo B, non-HDL-C, and TG, and increases HDL-C in patients with hyperlipidemia. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Available for Android and iOS devices. In phase one the main study endpoint was therefore the incidence of muscle-related side effects. Ezetimibe should be used during pregnancy only if the potential benefit justifies the risk to the fetus.In oral (gavage) embryo-fetal development studies of Ezetimibe conducted in rats and rabbits during organogenesis, there was no evidence of embryolethal effects at the doses tested (250, 500, 1000 mg/kg/day). They were then randomised to either inactive placebo or a "re-challenge" with atorvastatin (20mg) for 10 weeks. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.Examples of drugs that can cause interactions with ezetimibe are listed below.Taking certain cholesterol-lowering drugs with ezetimibe can decrease the amount of ezetimibe in your body. This condition is … However, myopathy and rhabdomyolysis are known adverse reactions to statins and other lipid-lowering drugs. It comes as an oral tablet.Ezetimibe oral tablet is available as the brand-name drug Zetia. Ezetimibe is a safe and efficacious non-statin LDL-C-lowering agent particularly in high-risk patients, such as those post-ACS. However, a dose of 300 mg/kg/day administered to dogs for one year did not result in gallstone formation or any other adverse hepatobiliary effects. A person had a significantly higher risk of developing muscle-related side effects while taking atorvastatin than placebo. This narrowing can slow or block blood flow to your heart, brain, and other organs. Therapy with lipid-altering agents should be only one component of multiple risk factor intervention in individuals at significantly increased risk for atherosclerotic vascular disease due to hypercholesterolemia. This reduces cholesterol in your liver and blood.Ezetimibe oral tablet can cause drowsiness. Approaches may include using very low-dose statins, giving statins intermittently, or alternatively giving non-statin treatments. Intestinal cholesterol is derived primarily from cholesterol secreted in the bile and from dietary cholesterol.Ezetimibe has a mechanism of action that differs from those of other classes of cholesterol-reducing compounds (statins, bile acid sequestrants [resins], fibric acid derivatives, and plant stanols). These elevations in transaminases were generally asymptomatic, not associated with cholestasis, and returned to baseline after discontinuation of therapy or with continued treatment. Because many drugs are excreted in human milk, caution should be exercised when Ezetimibe is administered to a nursing woman. Cyclosporine concentrations should be monitored in patients receiving Ezetimibe and cyclosporine.The degree of increase in Ezetimibe exposure may be greater in patients with severe renal insufficiency.