2020 Jan;45(1):73-75. doi: 10.30476/ijms.2019.81954.Recent Pat Inflamm Allergy Drug Discov. Schober J, Dulabon L, Martin-Alguacil N, Kow LM, Pfaff D.J Pediatr Adolesc Gynecol. Surgical treatment should be avoided if at all possible and considered only as a last resort.Recurrence rates are high. Recurrence rates range between 10–16%, depending on the treatment.Labial fusion is a relatively common condition that can cause significant distress to parents because of worries regarding the normality of their daughter's genitalia. Surgical treatment based on an accurate anatomic assessment may be needed, but the usefulness of endoscopic examination for this disease has not been reported. It is most common in girls less than 2 years of age. Clipboard, Search History, and several other advanced features are temporarily unavailable. Five patients developed vulval pigmentation, which lasted for a mean of 1.5 months. The introital area was carefully rinsed twice each day before application of either the estrogen cream or the petroleum ointment. Avoiding local irritants, such as bubble bath, and choosing cotton rather than synthetic underwear is also advisable. We conclude that treatment of labial fusion with topical estrogen therapy is safe and effective. Labial adhesions have been associated with lichen sclerosus, in which adhesions are characteristically dense and difficult to treat and can persist into puberty and adulthood.Unusual infections such as severe herpes and graft versus host disease have also been associated with labial adhesions and can occur in older patients.In the past there has been debate as to whether labial adhesions can be caused by sexual abuse. Vulvovaginitis, diarrhoea and scratching of the vulva can lead to local trauma of the skin with superficial denudement of the labia. One patient developed breast enlargement, which lasted for 1 month. All of these effects regress promptly after discontinuation of the medication.Based on observations on male children with phimosis, where local application of steroids can lead to resolution of the problem,Where medical treatment has failed, and if there are associated urinary symptoms, surgical correction may be indicated. Name must be less than 100 characters Unable to load your collection due to an error The mean duration of estrogen treatment was 2.4 months (range, 1 to 3.5 months). The labial adhesions will resolve naturally when endogenous estrogen production starts, usually before the age of 9 years. According to a survey of parents whose children had undergone separation of labial adhesions under local anaesthetic, the perception of their child's discomfort was rated as moderate or severe in half of the cases.In those few cases where surgical treatment is required, this should be carried out under a brief general anaesthetic. The mean duration of follow-up was 3.1 months, and there was no recurrence of labial fusion during the period of follow-up. In a study of the genitalia of 9070 newborns,The skin of the vulva prior to puberty is fragile and thin and, as a result, is prone to infection and inflammation. Treating labial fusion. A 76-year-old Japanese woman undergoing chemoradiation treatment for esophageal cancer was referred to our … The cream was precisely applied to the fused area twice a day until the adhesions were totally lysed. 2018 Mar 8;18(1):104. doi: 10.1186/s12887-018-1018-x.Geburtshilfe Frauenheilkd. The condition resolves with the onset of puberty.To be able to reassure parents that the condition is self‐limiting and benign.To know the treatment modalities available for symptomatic children.There is no evidence that child sexual abuse causes labial adhesions, however, if the presentation is atypical or there are other concerns, advice should be sought from the lead professional for child protection in the organisation or Trust.Please cite this article as: Michala L, Creighton SM.