Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain (), heart failure, and esophageal spasms. You may also need to take extra medicines to reduce this risk. isosorbide mononitrate oral brand names and other generic formulations include: Imdur Oral, Ismo Oral, Isotrate ER Oral, Monoket Oral. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Just wondering if it would be worth me asking my doctor for Viagra. In addition, each tablet contains the … Very common: Headache predominates (up to 30%) necessitating withdrawal of 2 to 3% of patients, but the incidence reduces rapidly as treatment continues.Common: Tiredness, sleep disturbances (6%) and gastrointestinal disturbances (6%) have been reported during clinical trials with isosorbide mononitrate modified-release tablets, but at a frequency no greater than for placebo. Can Viagra be taken with Isosorbide Mononitrate, Quinapril, Atorvastatin and Metoprolol? Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Please check with a physician if you have health questions or concerns. We earn a commission for products purchased through some links in this article. Both nicorandil and isosorbide mononitrate can increase the risk of hypotension. If you are taking these medicines and you experience an angina attack, you must go to the hospital right away. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Nicordanil is also used for angina. Isosorbide mononitrate is a drug that is prescribed for the treatment of angina pectoris. If you have severe pain, talk with your doctor. Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Blood tests may be needed to check for unwanted effects. Medicines to prevent hearts attacks and strokes. If you can't have either of these medicines, you may be given another medicine such as ivabradine, nicorandil or ranolazine. Portions of this document last updated: Aug. 01, 2020Copyright © 2020 IBM Watson Health. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. It was patented in 1971 and approved for medical use in 1981.The following adverse effects have been reported in studies with isosorbide mononitrate: This tool may not cover all possible drug interactions. These headaches are a sign that the medicine is working. Abnormal heart sound Ketoprofen. Dizziness, lightheadedness, or faintness may occur, especially when you get up quickly from a lying or sitting position. While you are taking this medicine, be careful to limit the amount of alcohol you drink. Taking these medicines together can cause a sudden and serious decrease in blood pressure. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Do not take riociguat (Adempas®), sildenafil (Viagra®), tadalafil (Cialis®), or vardenafil (Levitra®) while you are using this medicine. Do not stop using the medicine or change the time you use it in order to avoid the headaches. Nicorandil is predicted to increase the risk of gastrointestinal perforation when given with ketoprofen. Posted on Tue, 27 Sep 2016 . This medicine may cause headaches. Also, use extra care during exercise or hot weather or if you must stand for long periods of time. It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Check with your doctor immediately if any of the following side effects occur while taking isosorbide mononitrate: Less common. Our general interest e-newsletter keeps you up to date on a wide variety of health topics.If you will be taking this medicine for a long time, it is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. 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