Hyperhidrosis (HH) is characterized by excessive sweat production. Febrile diseases: acute and chronic infections, and neoplasiaMetabolic: thyrotoxicosis, diabetes mellitus, hypoglycemia, gout, pheochromocytoma, hyperpituitarism, or menopauseSympathetic discharge: shock and syncope, intense pain, alcohol, and drug withdrawalNeurologic: Riley-Day syndrome, irritative hypothalamic lesionsDrugs: propranolol, physostigmine, pilocarpine, tricyclic antidepressants, or venlafaxineGustatory: citric acid, coffee, chocolate, peanut butter, and spicy foodsPrimary or essential hyperhidrosis is a disorder that causes hyperhidrosis of the hands, feet, and sometimes the axillae. After 48 hours of use, the pain completely disappeared. The causes and conditions associated with localized hyperhidrosis include primary palmoplantar hyperhidrosis, unilateral circumscribed hyperhidrosis, hyperhidrosis associated with intrathoracic neoplasms, olfactory hyperhidrosis, gustatory hyperhidrosis, spinal cord injuries, and Frey's syndrome. Patients were assigned randomly to receive 2.5, 5 or 10 mg/kg of zinc sulphate orally, and a control group of patients did not receive any treatment. It is estimated that 0.6% to 1.0% of the population suffers from this problem. It may be primary (idiopathic, essential) or secondary to a number of diseases and prescribed drugs. Axillary sweating may be the result of both emotional and thermal stimuli.The causes for generalized hyperhidrosis (Display Box 1) include a number of febrile illnesses, neoplastic and neurologic diseases, metabolic disorders, and drugs. Although primary or essential hyperhidrosis is the most common cause of palmoplantar hyperhidrosis it may also occur in some patients with Raynaud's disease, rheumatoid arthritis, erythromelalgia, nail patella syndrome, keratosis palmaris et plantaris with clindactyly, atrioventricular fistula, and cold injury. Anxiety about social situations and relationships, and problems with daily … All patients were followed up for 45 days. Glycopyrrolate tablets are also added to the solution used for iontophoresis for reducing excessive sweating from hands and feet. In 2017, a randomized controlled trial was conducted on 29 patients with hyperhidrosis. Eczema, Psoriasis. 0.5 % g lycopyrrolate solution or topical glycopyrrolate applied daily helps to reduce craniofacial hyperhidrosis. Chloramphenical 0.5% drops Chloramphenical 1% ointment Optrex Golden eye Lumicare Cold sores Antiviral cold sore cream Aciclovir cream 5% Virasorb Zovirax Lypsyl Coughs, colds & nasal congestion Cough mixtures or linctus, saline nose drops, menthol vapour rubs, cold and flu capsules or sachets Lemsip Olbas Oil Benylin Robitussin Haemorrhoids ScienceDirect ® is a registered trademark of Elsevier B.V.Copyright © 1998 W. B. Saunders Company. It seems that in patients with primary hyperhidrosis, the hypothalamic sweat centers are more sensitive to emotional stimuli of cerebral origin than in ordinary people. Herpes (Zoster, Genital, Simplex) Alclometasone. Axillary and plantar hyperhidrosis may result in stains and damage to clothing and shoes. Regardless of the type or cause of the hyperhidrosis, it is frequently socially embarrassing and occupationally disabling. Careers in fields that require contact with paper, metal, and electrical components become unrealizable. Topical medication, breaks up comedones. #### Summary points Primary hyperhidrosis is characterised by sweating in excess of that needed for normal thermoregulation.1 The condition often goes unreported because of embarrassment,2 and management is hindered by a poor evidence base and lack of clinical guidelines. Although primary or essential hyperhidrosis is the most common cause of palmoplantar hyperhidrosis it may also occur in some patients with Raynaud's disease, rheumatoid arthritis, erythromelalgia, nail patella syndrome, keratosis palmaris et plantaris with clindactyly, atrioventricular fistula, and cold injury.