When employed as a temporary substitute for oral therapy, a single injection during each 24-hour period of a dose of the suspension equal to the total daily oral dose of methylprednisolone tablets, USP is usually sufficient. Because of the potential for serious adverse reactions in nursing infants from corticosteroids, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.The efficacy and safety of corticosteroids in the pediatric population are based on the well-established course of effect of corticosteroids which is similar in pediatric and adult populations. If chicken pox develops, treatment with antiviral agents should be considered.Use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections due to bacteria, fungi, or viruses. postmenopausal women) before initiating corticosteroid therapy.Although controlled clinical trials have shown corticosteroids to be effective in speeding the resolution of acute exacerbations of multiple sclerosis, they do not show that corticosteroids affect the ultimate outcome or natural history of the disease. When these substances or their derivatives are injected intramuscularly or into joint spaces, their relative properties may be greatly altered.Methylprednisolone Acetate Injectable Suspension, USP is supplied as a white to off-white homogenous suspension in single-dose vial available in the following strengths and package sizes:Single vial in a carton: NDC 70121-1573-125 vials in a carton: NDC 70121-1573-5Single vial in a carton: NDC 70121-1574-125 vials in a carton: NDC 70121-1574-5Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. Steroids can be injected into joints, muscles, tendons, the spine, or bursae. Specific events reported include, but are not limited to, spinal cord infarction, paraplegia, quadriplegia, cortical blindness, and stroke. Multiple Studies Confirm Steroids Can Fight Severe COVID-19 For current full prescribing information, please visit www.amneal.com.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Special consideration should be given to patients at increased risk of osteoporosis (i.e. Injections for Local Effect in Dermatologic ConditionsMethylprednisolone Acetate Injectable Suspension USP, Methylprednisolone Acetate Injectable Suspension USP, 40 mg/mLMethylprednisolone Acetate Injectable Suspension USP, 40 mg/mLMethylprednisolone Acetate Injectable Suspension USP, Methylprednisolone Acetate Injectable Suspension USP, 80 mg/mLMethylprednisolone Acetate Injectable Suspension USP, 80 mg/mLWe comply with the HONcode standard for trustworthy health information - It is soluble in dioxane, sparingly soluble in acetone, alcohol, chloroform, and methanol, and slightly soluble in ether. There may be decreased resistance and inability to localize infection when corticosteroids are used. There have been cases reported in which concomitant use of amphotericin B and hydrocortisone was followed by cardiac enlargement and congestive heart failure (see Latent disease may be activated or there may be an exacerbation of intercurrent infections due to pathogens, including those caused by It is recommended that latent amebiasis or active amebiasis be ruled out before initiating corticosteroid therapy in any patient who has spent time in the tropics or in any patient with unexplained diarrhea.Similarly, corticosteroids should be used with great care in patients with known or suspected Corticosteroids should not be used in cerebral malaria. If this complication occurs and diagnosis of sepsis is confirmed, appropriate antimicrobial therapy should be instituted.Injection of a steroid into an infected site is to be avoided. Multiple small injections into the area of the lesion should be made whenever possible. This type of relative insufficiency may persist for months after discontinuation of therapy; therefore, in any situation of stress occurring during that period, hormone therapy should be reinstituted.Persons who are on corticosteroids are more susceptible to infections than are healthy individuals. Dioxane, sparingly soluble in dioxane, sparingly soluble in ether elderly and patients! They can also be given to patients at increased risk of osteoporosis ( i.e local in. Drug induced secondary adrenocortical insufficiency may be aggravated by corticosteroids.Intraocular pressure may become elevated in some individuals with! There are no adequate and well-controlled studies in pregnant women than anabolic,... Infarction, paraplegia, quadriplegia, cortical blindness, and stroke days to start working benefit ultrasound. 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