Sumatriptan injection, USP is indicated in adults for (1) the acute treatment of migraine, with or without aura, and (2) the acute treatment of cluster headache. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme, website: www.mhra.gov.uk/yellowcard.There have been some reports of overdosage with Sumatriptan.Patients have received single injections of up to 12 mg subcutaneously without significant adverse effects.Doses in excess of 16 mg subcutaneously were not associated with side effects other than those mentioned.If overdosage with Sumatriptan occurs, the patient should be monitored for at least ten hours and standard supportive treatment applied as required.It is unknown what effect haemodialysis or peritoneal dialysis has on the plasma concentrations of sumatriptan.Pharmacotherapeutic group: analgesics; antimigraine preparations; selective serotonin (5-HTSumatriptan has been demonstrated to be a specific and selective 5-hydroxytryptamine (5-HTSumatriptan remains effective in treating menstrual migraine i.e. The diagnosis of medication overuse headache (MOH) should be suspected in patients who have frequent or daily headaches despite (or because of) the regular use of headache medicationsThere is no evidence of interactions with propranolol, flunarizine, pizotifen or alcohol.There are limited data on an interaction with preparations containing ergotamine or another triptan/5-HTThe period of time that should elapse between the use of sumatriptan and ergotamine-containing preparations or another triptan/5-HTAn interaction may occur between sumatriptan and MAOIs and concomitant administration is contra-indicated (see section 4.3).There have been rare post-marketing reports describing patients with serotonin syndrome (including altered mental status, autonomic instability and neuromuscular abnormalities) following the use of SSRIs and sumatriptan. By continuing to browse the site you are agreeing to our policy on the use of cookies. Drowsiness may occur as a result of migraine or its treatment with sumatriptan. Each pre-filled pen contains 6 mg of sumatriptan, as sumatriptan succinate. Administration during a migraine aura prior to other symptoms occurring may not prevent the development of a headache.It is recommended to start the treatment at the first sign of a migraine headache, cluster headache or associated symptoms such as nausea, vomiting or photophobia. After removal of the needle shield, the open end of the pre-filled pen is to be placed on the injection site, straight up at a right angle (90°). Continue typing to refine. Some of the symptoms reported as undesirable effects may be associated symptoms of migraine.Not known: Hypersensitivity reactions ranging from cutaneous hypersensitivity (such as urticaria) to anaphylaxis.Common: Dizziness, drowsiness, sensory disturbance including paraesthesia and hypoaesthesia.Not known: Seizures, although some have occurred in patients with either a history of seizures or concurrent conditions predisposing to seizures. Sumatriptan Injection should not be used prophylactically. When suggestions are available use up and down arrows to review and ENTER to select. The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine. Patients should be advised to strictly observe the instruction leaflet for Sumatriptan SUN especially regarding the use of the pre-filled pen.Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.Sumatriptan should not be given to patients who have had myocardial infarction or have ischaemic heart disease, coronary vasospasm (Prinzmetal's angina), peripheral vascular disease or patients who have symptoms or signs consistent with ischaemic heart disease.Sumatriptan should not be administered to patients with a history of cerebovascular accident (CVA) or transient ischaemic attack (TIA).Sumatriptan should not be administered to patients with severe hepatic impairment.The use of sumatriptan in patients with moderate and severe hypertension and mild uncontrolled hypertension is contraindicated.The concomitant administration of ergotamine or derivatives of ergotamine (including methysergide) or any triptan/5-hydroxytryptamineConcurrent administration of monoamine oxidase inhibitors and sumatriptan is contraindicated.Sumatriptan must not be used within two weeks of discontinuation of therapy with monoamine oxidase inhibitors (see section 4.5).Sumatriptan SUN should only be used where there is a clear diagnosis of migraine or cluster headache.Sumatriptan is not indicated for use in the management of hemiplegic, basilar or opthalmoplegic migraine.The recommended doses of Sumatriptan should not be exceeded.This medicinal product contains less than 1 mmol sodium (23mg) per dose, i.e. Injection is complete and to operate machinery.Adverse events are listed below by system organ class and frequency skin a...: 1, 2, 6 or 12 pre-filled pens given intravenously, because its! 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