The Sinclair Method (TSM) is a treatment for alcohol addiction that uses a technique called pharmacological extinction—the use of an opiate blocker to turn habit-forming behaviors into habit erasing behaviors. And unlike disulfiram, the opioid antagonists do not produce an unpleasant aversive effect.

00. Cymbalta (duloxetine) is a selective serotonin and norepinephrine reuptake inhibitor antidepressant (SSNRI).Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. So a solution to stopping the reinforcement cycle might be to block the receptors every time alcohol was used. Understand and think about addiction in an entirely new way.Step Three. Naltrexone, Naloxone, and Nalmefene are not substitution drugs similar to Methadone for heroin addiction or Nicorettes™ for nicotine addiction. An introduction to the 5 steps of the Sinclair Method from the book "the Cure For Alcoholism" by Dr Roy Eskapa. The Sinclair Method represents just another easier, softer way, as referenced in the Big Book, that the alcoholic uses to try and control his drinking rather than looking to a spiritual solution to cease drinking altogether. The effect returns a person’s craving for alcohol to its pre-addiction state. The Sinclair Method (TSM) is a truly unique approach to tackling alcohol addiction or the problem of excessive drinking. Indeed, the opioid antagonists do not do anything until after endorphin has been released. Sinclair tested his theory on rats using naltrexone, an opiate blocker, and after that he conducted clinical trials in people.

The effect returns a person’s craving for alcohol to its pre-addiction state.In a few months, most people can cut down their alcohol consumption to safe levels and many stop drinking alcohol for good. You should consult with a healthcare professional before taking any medication, or if you have or suspect you might have a health problem. The conventional approach is to quit drinking completely to live a ‘normal life’, but the Sinclair Method (TSM) aims to give you control. Kindle $0.00 $ 0. About the Sinclair Method The Sinclair Method (TSM) is a treatment for alcohol addiction that uses a technique called pharmacological extinction—the use of an opiate blocker to turn habit-forming behaviors into habit-erasing behaviors. TSM consists of taking an opiate blocker one hour before… You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. Prime members enjoy FREE Delivery and exclusive access to music, movies, TV shows, original audio series, and Kindle books. This is called “extinction” and Sinclair thought the learned behavior of an addiction to alcohol could be removed by extinction, too.Following his early research, Sinclair hypothesized that alcohol produces reinforcement in the brain in a way that’s similar to opiates. The results were  encouraging.The solution discovered by Sinclair effectively means you have to drink yourself sober! Then the mechanism of extinction is triggered, and the extinction mechanism in turn progressively but permanently removes the neural cause for excessive drinking.Legal Disclaimer Notice: The rules for obtaining opioid antagonist tablets such as Naltrexone vary in different parts of the world so always consult your Doctor. That alcoholism is a learned behavior. It describes the method itself, including the pharmacology of the medication Naltrexone and an extensive collection of published scientific articles. Your recently viewed items and featured recommendations Once conditioned, dogs rewarded with food after a bell had been rung would salivate at the sound of the bell itself. Your Prescription for Naltrexone or NalmefeneExcerpt pp 67-69/ The United States Still Lacks Knowledge About NaltrexoneWhat Does It Feel Like to Drink While Taking Naltrexone?Richard’s Story: The Sinclair “Lite” Method—Same Great Success, Less IntensiveStep One. The-Sinclair-Method.com describes the research by Dr David Sinclair on the treatment for Alcoholism "The Sinclair Method" , that makes use of an extinction method using an opioid antagonist such as Naltrexone, before consuming alcohol. Over time, the desire to consume alcohol will diminish and people end up abstaining most of the time or occasionally have a drink when they wish. Cymbalta is used to treat major depressive disorder in adults. The Sinclair Method: So how does it Work? You need to continue taking the medication before drinking, even when you feel things are under control.Just take a tablet one to two hours before drinking Claudia Christian gave a Ted talk about "The Sinclair Method" Key People in the development and publicity of The Sinclair Method.The film features contributions from Dr David Sinclair and other people invloved in the research as well as people who have benefited from using the method.