If you suspect an overdose, seek emergency veterinary help before the symptoms have a chance to progress. For dogs, theophylline is dosed at 3 to 5 mg per pound (6 to 10 mg/kg) three times daily; higher doses may be prescribed with the twice-daily extended action preparations. The medication should be administered on an empty stomach and food should be given an hour after the administration of the medication. Care should be taken to ensure that dogs are weighed carefully and accurately, and the dose does not exceed 20 mg/kg body weight. Theophylline is rapidly and completely absorbed after oral administration in solution or immediate-release solid oral dosage form. After a single dose of 5 mg/kg in adults, a mean peak serum concentration of about 10 mcg/mL (range 5-15 mcg/mL) can be expected 1-2 hrs after the dose. Wellness Advice Never give your pet two doses at once or give extra doses.The most common side effects include central nervous system stimulation (excitement) and stomach or intestinal irritation such as nausea, vomiting, and diarrhea. Theophylline, the active ingredient contained in the medication helps in relaxing the muscles in and around the windpipe, thereby dealing with the breathing complications due to The medication is safe to be used in dogs and cats. Bronchodilators such as theophylline may be used with corticosteroids, and the use of a bronchodilator may permit a lowering of the dose of the corticosteroids. Contact your veterinarian immediately if you observe these side effects in your pet.This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver disease or congestive heart failure.Theophylline should not be used in pets that are sensitive or allergic to it, or related substances such as theobromine, aminophylline, or caffeine. Overdose (symptoms, emergency procedures, antidotes), if necessary There is no specific treatment for theophylline overdose in the dog. Theophylline works to clear passages to your pets' lungs and keep them healthy. The medication should be administered on an empty stomach and food should be given an hour after the administration of the medication. Medications Its use in cats and dogs to treat cough and bronchoconstriction is Theophylline is given by mouth in the form of a tablet or liquid, with or without food. The medication should be administered on an empty stomach and food should be given an hour after the administration of the medication. Hello my name is***** but you can call me Dr. H, and I am a licensed veterinarian. Give the medicine on an empty stomach, which is an hour before or 2 hours after food intake. Do not crush or break the tablets or allow your pet to chew them.This medication should take effect within 1 to 2 days, and you should see improvements in your pet’s clinical signs.If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time, and return to the regular dosing schedule. During treatment the dog will need to be carefully monitored, both for the r… The medication is also contraindicated in pets suffering from gastric ulcers, epilepsy, liver disease, kidney disease, congestive heart failure, hypothyroidism or fluid in the lungs.Theophylline should not be given in conjunction with other medications such as Enroflaxacin, cimetidine, clindamycin, erythromycin, lincomycin and allupurinol as these medications can increase the blood levels of Theophylline and increase its efficacy.Theophylline is also contraindicated in conjunction with Phenobarbital as its efficacy is reduced by Phenobarbital. In case of long active tablets, the prescribed dosage for dogs is 10mg/lbs. Be careful not to administer an overdose of this drug, as overdose symptoms can be very serious, leading to tremors, seizures and an uneven heartbeat. Other side effects include sleeplessness, increased drinking, eating, and urinating.Severe toxic effects can occur but are rare.