This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of iontophoretically-applied acyclovir 5% cream for the treatment of herpes simplex labialis lesions including an open label arm using Zovirax (acyclovir) Cream 5% as per standard of care in the same patient population. By continuing to use this site you consent to the use of cookies on your device as described in our cookie policy unless you have disabled them. Get it as soon as Thu, Jul 23. There are no reports concerning an overdose of aciclovir cream.No untoward effects would be expected if the entire contents of a 20g tube of the cream were ingested. Currently operating in 300+ cities, with 1800 offline stores in India, MedPlus is the second largest pharmacy chain in India today. Continue typing to refine. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.Overdose is unlikely to occur, if the cream is applied locally and as indicated. Other drugs affecting renal physiology could potentially influence the pharmacokinetics of aciclovir. This is also confirmed by histologic studies and autopsy. It is used to stop or treat herpes infections. Amazon's Choice for acyclovir cream. Alert your doctor if you ever had an allergic reaction (rashes, swollen eyes, mouth or breathlessness) to similar medicines such as famciclovir, valacyclovir, or any of the ingredients of acyclovir. Signs of a very bad reaction to the drug include wheezing, chest tightness, fever, itching, bad cough, blue or gray skin color, seizures, or swelling of face, lips, tongue, or throat.Alert your doctor if you are taking any of these medicines: Gastric medicines such as cimetidine; Probenecid; Theophylline (for asthma); Diuretics (water pills - used to treat heart disease or high blood pressure; Transplant medicines such as mycophenolate mofetil, cyclosporin or tacrolimus. This site uses cookies. The clinical relevance of these findings is uncertain.Largely reversible adverse effects on spermatogenesis in association with overall toxicity in rats and dogs have been reported only at doses greatly in excess of those employed therapeutically. Do not skip any doses. This product is not recommended for use in immunocompromised patients.Treatment should be initiated as soon as possible after the start of the infection, ideally during the prodromal period or when the lesions first appear.A thin film of cream should be applied to the infected and immediately adjacent skin areas 5 times daily at 4 hour intervals during the day omitting the night time application.Treatment should be continued for 5 days, followed by a further 5 days treatment if healing has not occurred.Patients should wash their hands before and after applying the cream, and avoid unnecessary rubbing of the lesion or touching them with a towel, to avoid aggravating or transferring the infection.Hypersensitivity to aciclovir, valaciclovir, propylene glycol or any other ingredients of the preparation listed in Section 6.1.In severely immunocompromised patients (e.g. Find patient medical information for Acyclovir Topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. According to the test carried out by Draize, who evaluated the allergic sensitising potential of a substance there were no pathologic findings.Studies carried out in swine showed that 5% aciclovir cream in a PEG vehicle caused an only minimal (quantitative) delay in epidermal wound healing.Rabbits had 1, 3 or 6% aciclovir cream in a white petroleum vehicle introduced directly into both eyes 5 times daily at 90-minute intervals for 3 weeks. Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions. When suggestions are available use up and down arrows to review and ENTER to select. Particular care must be taken to avoid contact with the eye.The excipient propylene glycol can cause skin irritations.The excipient cetyl alcohol can cause local skin reactions(e.g. Single intravenous doses of up to 80mg/kg have been inadvertently administered without adverse effects. There were neither systemic nor local toxic symptom. If you dont, the infection will not clear completely. The tubes are packed individually into cardboard boxes together with package leaflets.42-46 Booth Drive, Park Farm South, Wellingborough, Northamptonshire, NN8 6GTTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. in the oral cavity, the eye or the vagina), as local irritation may occur. $22.47 $ 22. • You must contact a doctor if your symptoms worsen or do not improve. Continue to take it even when you feel better. You may need to read it again. Aciclovir cream 5% Read all of this leaflet carefully because it contains important information for you. AIDS patients or recipients of bone marrow transplants) oral dosing should be considered. Number with usYes I would like to be updated of new promotional offers the infection not. It allows continued monitoring of the body surface the benefit/risk balance of benefit/risk... 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