* Approximation only. Severe Interactions. Contact your doctor right away if you experience easy excitability, agitation, loss of coordination, fast heartbeat, sweating, muscle spasms or seizures, or if you have any thoughts of suicide.If your tramadol is not working, contact your healthcare professionals.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Does Tegretol Tablet Interact with other Medications? Patients taking carbamazepine, a CYP3A4 inducer, may have a significantly reduced analgesic effect of tramadol. The study is created by eHealthMe based on reports of 88 people who take Tramadol hydrochloride and Carbamazepine from the Food and Drug Administration (FDA), and is updated regularly. CYP3A4 is the most important of the CYP450 enzymes for drug metabolism and for drug interactions. Drug interactions are reported among people who take Tramadol hydrochloride and Carbamazepine together. This information is generalized and not intended as specific medical advice. Since Tegretol ( Carbamazepine) is one of the most powerful liver enzyme inducers. All rights reserved. Drug Interactions . Tapentadol, tramadol, … Tapentadol, tramadol, and tricyclic compounds also affect the amount of serotonin in your brain. Comprehensive alcohol & food interactions for Tramal (tramadol). Carbamazepine may increase how quickly your liver processes tramadol.You may be at risk of having a seizure if you take tramadol with a tricyclic compound or carbamazepine.If you take tapentadol or tramadol with a tricyclic compound, you may be at risk of developing a potentially life-threatening condition called serotonin syndrome and your risk of suicide may increase.If you take tramadol with carbamazepine, it may not work as well in in controlling your pain.Let your healthcare professionals (e.g. Drs. For an electronic version of this article, including references if any, visit www.hanstenandhorn.com. These medicines may interact and cause very harmful effects. Do not start, stop, or change the dosage of any medicine before checking with them first.Selected from data included with permission and copyrighted by First Databank, Inc. When taken along with Tramadol (an opioid pain killer), Tegretol enhances the metabolism (clearance) of Tramadol from the body thereby decreasing its blood levels and thus reducing its efficacy in relieving the pain. It is recommended that patients use the information presented as a part of a broader decision-making process.If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.© 2020 eHealthMe.com. doctor or pharmacist) know that you are taking these medicines together. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.Serious. Consult your healthcare professional (e.g., doctor or … Examples: Rifampin, carbamazepine, phenytoin doctor or pharmacist) for more information.Tramadol, tricyclic compounds, and carbamazepine can increase your risk of having a seizure. ... Tramadol Trazodone Tucatinib Ubrogepant Ulipristal Upadacitinib Valbenazine ... efavirenz, Atripla®, Sustiva®, Rescriptor®). Horn and Hansten are both professors of pharmacy at the University of Washington School of Pharmacy. Because carbamazepine increases tramadol metabolism and because of the seizure risk associated with tramadol, concomitant administration of Ultram and carbamazepine is not recommended. • Tramadol • Tricyclic antidepressants • Triptans ... Carbamazepine Clopidogrel Efavirenz Lopinavir Phenobarbital Phenytoin Ritonavir ... Alcohol Carbamazepine Efavirenz Lopinavir Phenobarbital Phenytoin Ritonavir . 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