I already deal with GI issues so it made me more constipated and dropped it.Good to hear. The ad describes and illustrates depression as a "tangle" of multiple symptoms, which presumably Trintellix will somehow untangle. It only helps if I take it right before bed. I'm taking it for anxiety and depression and I've definitely noticed a difference. By using our Services or clicking I agree, you agree to our use of cookies. Just don’t know whether to accept that this may be as good as it gets.I literally just took my first dose and after 2 hours I started aggressively vomiting (you know the kind where you basically just loudly gargle "hyyyaaaaaarrrghhhhh" for 20 minutes).Is this just a fun one off start up thing or does it continue? Press question mark to learn the rest of the keyboard shortcuts I take my dose right before bed because of the nausea. I have emetophobia and am already terrified of leaving the house in case I vomit :(I've been on Trintellix 10mg for about 2 years now, and for some reason the nausea has come back with a vengeance.I'm just wanting to know what has worked for everyone in dealing with this.I bought some ginger tea and candies from Amazon as well as the ginger Gravol.A small community for patients using the drug Trintellix.Looks like you're using new Reddit on an old browser. No brain fog. I had never even heard of this medication until today. So it does work but I don’t feel a zest for life.The doctor said that the drug can only do so much which I do agree with. This sub is not for venting or for facebook style posts. It's hard to determine if the fatigue was actually being caused by Trintellix since I was previously on 120mg Cymbalta for over 7 months.Mood wise, Lexapro was superior but it also came with more side effects which is why is wasn't worth it for me. Recently (past few months), I’ve had HORRIBLE nausea after taking the pill and dizziness/vomiting. I knew of the nausea and dizziness, and with anything futzing with your brain chemistry you are going to experience headaches. Low quality posts will be removed.Press J to jump to the feed. Not because I’m nauseous. I am switching back to cipralex soon - can’t say I recommend TrintellixFor those of you that take this drug, do you feel motivated?My depression has lifted in the sense that I no longer feel hopeless and sad and overwhelmed by life but my Behaviour hasn’t changed. I personally couldn't stay on it, though, because I have bipolar type II, and it made me hypomanic.Trintellix is only a new version of SSRIs, probably with less sides but the same risks. What he liked best about Trintellix was that it was marketed as a medication with less side effects compared to other antidepressants and people reported less drowsiness while on it. Pristiq rated 7.0/10 vs Trintellix rated 6.0/10 in overall patient satisfaction. It has a long half-life, so it can take a while to get to a therapeutic/steady level in the body. It still causes them but they're more tolerable than Lexapro. Only problem with it was that it started causing significant lethargy so I had to discontinue it since no amount of exercise, caffeine or eating healthy fixed it. Trintellix is a selective serotonin reuptake inhibitor (SSRI) and Pristiq is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). Is it like your typical SSRI and takes a few weeks to take effect?How are you doing so far with the trintellix side effects?I've been on it for two weeks now and I like it a lot. I have a doctors appointment next week. I was on citalopram too and felt the low sex drive. Compare Effexor vs Trintellix head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. 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