The increased risk of UTIs and genital infections seemed to have a dose–response relationship for dapagliflozin only. Seven (13.5%) of 52 and 33 (18.8%) of 176 women with type 1 and in type 2 diabetes, respectively, had significant bacteriuria. A urinary tract infection is a bacterial infection that grows within the urinary tract – anywhere from the kidneys, the ureters, the bladder and through to the urethra.. Urinary tract infections can be a particular problem for people with diabetes as sugar in the urine makes for a fertile breeding ground for bacteria.. Search for other works by this author on:
Reprints or correspondence: Dr. Mario Bonadio, Infectious Diseases Section, University of Pisa, Ospedale S. Chiara, via Roma 55, 56100 Pisa, Italy (
In some of the studies mentioned above, the control group probably was comprised of patients with less-severe illness. Metabolic Unit, Department of Internal Medicine, University-Hospital
2015; 8: 129–136. Search for other works by this author on:
Urinary tract infections are a common burden in patients with diabetes. The Manitoba Diabetic Urinary Infection Study GroupDip-slide in patients at high risk of urinary tract infectionReport of the Expert Committee on the Diagnosis and Classification of Diabetes MellitusAsymptomatic bacteriuria in patients with diabetes mellitusAsymptomatic bacteriuria in patients with diabetes mellitusEffect of glucose and pH on uropathogenic and non-uropathogenic Risk factors for symptomatic urinary tract infection in women with diabetes mellitus. Search for other works by this author on:
Is Long-Term Oral Therapy for Treatment of Bone and Joint Infections Ready for Prime Time? A control group of 146 women without diabetes was also evaluated. Metabolic Unit, Department of Internal Medicine, University-Hospital
We observed a similar rate of ASB among patients with and patients without diabetes, possibly because most of our patients had disease that was well controlled (fasting blood glucose levels, 135 ± 33 mg/dL) and because they were receiving treatment at the time of study enrollment.In the present study, however, a significant correlation was found between HbA1c level and ASB in women with type 2 diabetes. Any queries (other than missing content) should be directed to the corresponding author for the article.Please check your email for instructions on resetting your password. The 3 largest studies—in which 400, 341, and 1072 outpatient women with diabetes were evaluated—showed ASB rates of 9.5%, 9.1%, and 7.9%, respectively [Our control group comprised women without diabetes, most of whom were receiving treatment at a cardiology clinic. Urinary tract infections . To exclude patients with diabetes from the group without diabetes, we confirmed that they had neither diabetes nor glycosuria.All patients were screened for significant bacteriuria, which was defined as the presence of at least 10Identification of urine isolates was performed using conventional methods, and the in vitro susceptibility to antimicrobial drugs was tested by the Kirby-Bauer disk diffusion method. Hudson Valley, New York
The frequency of significant bacteriuria was 17.5% (40 of 228) among women with diabetes and 18.5% (27 of 146) among women in the control group. The presence of higher glycated hemoglobin levels was the only significant risk factor for significant bacteriuria in women with type 2 diabetes. Pyuria was recognized in 35 of 40 bacteriuric women with diabetes and in 30 of 33 bacteriuric women without diabetes. If you do not receive an email within 10 minutes, your email address may not be registered, Urinary tract infection occurs with increased frequency and severity in patients with diabetes mellitus. Thinking Beyond Glycaemia: Are SGLT2 Inhibitors the Answer?, Comparative risk of genital infections associated with sodium‐glucose co‐transporter‐2 inhibitors, Efficacy and safety of combination therapy with SGLT2 and DPP4 inhibitors in the treatment of type 2 diabetes: A systematic review and meta-analysis, Management of Hyperglycemia in Type 2 Diabetes, 2018. This can be explained by hypothesizing that our bacteriuric women with type 2 diabetes had a bladder dysfunction associated with diabetic autonomic neuropathy more frequently than did bacteriuric women with diabetes in other studies. The women without diabetes had no history of recent bladder catheterization. Search for other works by this author on:
Thank you for submitting a comment on this article. There are certain aspects to diabetes that makes it a risk factor for getting urinary tract infection and additionally, diabetes may also predispose to certain complications.