Commonly confused with lichen sclerosus, lichen planus, unlike lichen sclerosus, often involves the vaginal mucosa. Vaginal synechiae formation and eventual vaginal stenosis make sexual intercourse impossible. While patients with erosions and erythema saw improvement in this study, those with vaginal stenosis did not significantly improve. Close more info about Vulvovaginal Disorders: Lichen Planus Among women with erosive vulvovaginal lichen planus, over 50% will relate a personal or family history of an autoimmune disorder (most commonly, diabetes mellitus, thyroid disease and celiac disease). and you may need to create a new Wiley Online Library account.Enter your email address below and we will send you your usernameIf the address matches an existing account you will receive an email with instructions to retrieve your username The vaginal pH is typically in the 5-6 range, with numerous inflammatory cells and immature parabasal and basal epithelial cells seen on microscopic examination. In erosive lichen planus, deep, painful, erythematous lesions appear in the posterior vestibule, often extending lateral to the labia minora. A band-like infiltrate of lymphocytes and colloid bodies will be seen in the basal layers of the epidermis. For women with vaginal involvement, hydrocortisone suppositories can be used. Occasionally, labial synechiae may be noted in children with urinary tract or vaginal infection. A 25-mg rectal suppository (or a compounded 25-mg intravaginal suppository) is inserted intravaginally twice daily. American College of Obstetricians and Gynecologists”. Some of the researchers argue that the condition doesn’t affect the development and the growth of the fetus in any way.This condition is one of those asymptomatic ones that only show their symptoms when the condition becomes worse. Specialty: Gynaecology Asherman's syndrome (AS), is an acquired uterine condition that occurs when scar tissue form inside the uterus and/or the cervix. Finally, women with lichen planus face the risk of vulvar squamous cell cancer. It's not certain what causes labial fusion, but it usually happens as a result of irritation or inflammation of the vaginal area, known as vaginitis. Some other cases are from women who have had an infection involving uterus or the instrumentation before pregnancy. (Comprehensive review of multiple treatment options and supportive measure and clinical outcomes for women with vulvovaginal lichen planus. No sponsor or advertiser has participated in, approved or paid for the content provided by Decision Support in Medicine LLC. Close more info about Vulvovaginal Disorders: Lichen Planus Lichen planus presents less frequently to gynecologists and dermatologists than does lichen sclerosus. The worst condition of this syndrome may lead to recurrent abortion of the fetus within the next 3-4 weeks of the pregnancy.Since the adhesions are like scars which are formed inside the cavity of the uterus, the scar tissue can cause cyclic pelvic pain from periods. (Vulvar Intra-epithelial Neoplasia (VIN) Neoplastic cells are confined to the surface epithelium of the vulva It is a premalignant condition < CIN The major factor is HPV (type 16, and 33) Incidence of invasive carcinoma 4%. What Is The Evidence For Specific Management and Treatment Recommendations? Further development of scars and adhesions can be prevented with regular use of dilators as demonstrated in a number of prospective studies. Labial fusion, Labial adhesion, Labial synechiae, Labial agglutination, Labial adherence, Gynatresia, Vulvar fusion, and Vulvar synechiae.